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Startup And Venture Ecosystem Lead in San Francisco

101 active opportunities · Updated October 2026

Explore current startup and venture ecosystem lead jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for an experienced, hands-on support leader to build and run the support and escalation motion for GPT-Rosalind and OpenAI’s life sciences customers. This is both a builder role and a frontline support role. You will work directly with customers, own complex cases, diagnose technical and operational issues, and coordinate cross-functional teams through resolution. You will also create the intake paths, playbooks, knowledge, tooling, and operating mechanisms needed to support life sciences workflows across ChatGPT, Codex, and the OpenAI API. You’ll partner closely with Account Directors, Product, Engineering and Forward Deployed Engineering, Security, Legal, and bioscience subject-matter experts. You will help customers receive coordinated, accurate answers while maintaining clear boundaries between technical support, scientific consultation, product feedback, and roadmap commitments. This role is an opportunity to define how OpenAI supports scientists and life sciences organizations as they adopt increasingly capable AI systems. In this role, you will: Work directly with Rosalind and life sciences customers, taking ownership of complex technical and operational support cases from intake through resolution. Serve as a critical escalation point and final line of defense for complex technical issues, partner

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. You’ll be responsible for: Working directly with customers to troubleshoot and resolve their most complex technical issues, including API failures, integration challenges, authentication errors, and production incidents. Providing end-to-end ownership through debugging logs, analyzing system behavior, reproducing issues, and

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. As employees in this role with work with many customers based on the East Coast, regularly weekday hours will commence at 6am Pacific. To comply with a U.S. government contract, applicants for this position must be U.

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a leader to build and scale our Support Engineering team, which will collaborate directly with our strategic enterprise accounts, our product and engineering teams, as well as our field teams to solve some of the most difficult technical problems faced by our customers. You will lead one of the best technical troubleshooting teams at OpenAI, and our customers and Engineering teams will look to you for technical guidance in addressing the most technically difficult issues in our environment. You will play an integral role in building knowledge within the team and be part of strategic initiatives for organizational and process improvements. Working directly with our most strategic customers - You will be crucial to the success of the most innovative, disruptive, and high-scale AI solutions being built with the OpenAI platform. This team will handle high difficulty situations and issues. The team will be global, providing 24x7 technical coverage for our customers. This will be an opportunity to build this new team from first principles - your leadership will determine the future of this organization. The ideal candidate will have a combination of technical capabilities mixed with strong leadership and systems building strength. This role is based in San Francisco, CA. We use a hybrid work model of 3 days

Artificial IntelligenceAIExcel
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. Within Premium Support, Dedicated Support Engineers combine deep technical troubleshooting with an enduring understanding of our most strategic customers’ architectures, critical workloads, and business priorities. Through proactive reliability work, ownership during incidents, and AI-powered support capabilities, we help customers operate successfully as their use of OpenAI grows. About the Role We’re looking for a senior leader to build and scale our Dedicated Support Engineering function globally. You will define its strategy, build the team, and establish how we deliver technically rigorous, proactive support for customers running some of the most complex and consequential workloads on OpenAI. This role combines organizational leadership, technical judgment, and executive customer engagement. You will establish a model in which DSEs develop deep customer context, independently advance difficult investigations, anticipate operational risks, and drive issues through resolution. You will also turn what the team learns into improvements that benefit customers across OpenAI. You should bring experience building technical organizations that maintain long-term accountability for enterprise customers. Leadership in Technical Account Management, enterprise Support Engineering, or a comparable technical customer function is particularly rel

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a Support Program Manager to join our Support Delivery team. This role is an exciting opportunity to help define and implement foundational support practices that will scale with OpenAI’s growth. You will lead efforts to establish new operational frameworks, driving process alignment with various internal teams, and leading tooling and automation projects. This position offers the chance to make a significant impact in shaping customer experience while collaborating across multiple teams. We’re looking for people who thrive at the intersection of project management, systems building, data science/data engineering/software engineering, team enablement, and customer advocacy – and enjoy working cross-functionally in a fast-paced, evolving environment. This role is based in San Francisco, CA, and follows a hybrid work model of 3 days in-office per week. Relocation assistance is available. In this role, you will: Lead support delivery programs for Tier 3 frontline delivery for our most strategic customers, including productivity and workflow improvements, team operations, and knowledge management for the Support Delivery team Partner with Support Delivery and cross-functional leadership to define the experience, stand up the program, manage pilots and rollout, and ensure premium operations and playbooks st

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a leader to build and scale our Support Engineering team, which will collaborate directly with our strategic enterprise accounts, our product and engineering teams, as well as our field teams to solve some of the most difficult technical problems faced by our customers. You will lead one of the best technical troubleshooting teams at OpenAI, and our customers and Engineering teams will look to you for technical guidance in addressing the most technically difficult issues in our environment. You will play an integral role in building knowledge within the team and be part of strategic initiatives for organizational and process improvements. Working directly with our most strategic customers - You will be crucial to the success of the most innovative, disruptive, and high-scale AI solutions being built with the OpenAI platform. This team will handle high difficulty situations and issues. The team will be global, providing 24x7 technical coverage for our customers. This will be an opportunity to build this new team from first principles - your leadership will determine the future of this organization. The ideal candidate will have a combination of technical capabilities mixed with strong leadership and systems building strength. This role is based in San Francisco, CA. We use a hybrid work model of 3 days

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a hands-on lead to build and run OpenAI's Incidents & Escalations function within User Operations. This is a player-coach role with a meaningful hands-on operating component. You will set the operating model and also step into active incidents and urgent escalations when needed, coordinating with on-call teams, driving clear ownership, supporting communications, and ensuring issues move through resolution and post-incident closure. During active incidents, you will coordinate with the relevant on-call teams and cross-functional responders across Engineering, Infrastructure, Support Delivery, Product, and Go-To-Market. You will help keep teams aligned, maintain timelines, clarify ownership, escalate when needed, and ensure internal, executive, customer-facing, and external communications are accurate and timely, including status page updates when required. For escalations, you will build and run the processes for tracking, triaging, mitigating, and resolving critical customer and user issues. After incidents and escalations, you will own the follow-through: retrospectives, root cause identification, action item tracking, trend analysis, and process improvements that reduce repeat issues over time. You will also help define the long-term operating model for incidents and escalations across Support D

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a Technical Program Manager to join our Senior Support Engineering team. This role is an exciting opportunity to help define and implement foundational support practices that will scale with OpenAI’s growth. You will lead efforts to establish new operational frameworks, driving process alignment with various internal teams, and leading tooling and automation projects. This position offers the chance to make a significant impact in shaping customer experience while collaborating across multiple teams. We’re looking for people who thrive at the intersection of project management, systems building, data science/data engineering/software engineering, team enablement, and customer advocacy – and enjoy working cross-functionally in a fast-paced, evolving environment. This role is based in San Francisco, CA, and follows a hybrid work model of 3 days in-office per week. Relocation assistance is available. In this role, you will: Lead support delivery programs for Tier 3 frontline delivery for our most strategic customers, including productivity and workflow improvements, team operations, and knowledge management for the Support Delivery team Partner with Support Delivery and cross-functional leadership to define the experience, stand up the program, manage pilots and rollout, and ensure premium operations and

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s User Operations team shepherds our customers’ adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others, to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We’re looking for dedicated, experienced, and deeply curious individuals to help solve some of the most complex challenges faced by our customers while building the future of post-AGI support alongside us. In this role, you’ll work directly with customers through support tickets and live calls, troubleshooting high-impact issues and resolving novel, often ambiguous technical problems in one of the fastest-moving environments in technology. As AI adoption rapidly accelerates, the work you do will directly support mission-critical systems being built on OpenAI’s platform, serving as a critical line of defense for customers operating at massive scale. Beyond resolving technical issues, you’ll help define what world-class support looks like in an AGI-driven future. You’ll partner closely with Engineering, Product, and Operations to improve systems, reduce bugs, and elevate the customer experience, while leveraging automation, agents, and our own AI technology to transform how support operates at scale. You’ll be responsible for: Working directly with customers to troubleshoot and resolve their most complex technical issues, including API failures, integration challenges, authentication errors, and production incidents. Providing end-to-end ownership through debugging logs, analyzing system behavior, reproducing issues, and

PythonAWSRestAI
B
📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$240K – $285K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Why join us Brex is the AI-powered spend platform. We help companies spend with confidence with integrated corporate cards, banking, and global payments, plus intuitive software for travel and expenses. Tens of thousands of companies from startups to enterprises — including DoorDash, Flexport, and Compass — use Brex to proactively control spend, reduce costs, and increase efficiency on a global scale. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We're committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Engineering at Brex Engineering at Brex is about building systems that scale with speed and intention. Our teams span Software, Data, Security, and IT,

AIExcelAccountingFinance
S
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -87.9%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team The Support Experience group develops and applies technology at all points of the user support journey to solve customer problems at scale, keeping millions of businesses running and unlocking growth across Stripe’s product suite. What you’ll do The rise of AI agents has fundamentally changed how users interact with Stripe, with a supermajority of conversations with Stripe now occurring via AI across various surfaces including third-party platforms. These conversations now blend planning, building, configuration, and troubleshooting. As a Product Manager for Support Experience, you will be responsible for building the platform that enables Stripe’s user-facing AI agent to solve problems across the Stripe product suite. You’ll develop rapid AI-powered feedback loops that enable product teams across Stripe to continuously improve the conversational experience of their users and build the infrastructure to enable powerful and flexible conversational experiences to run in diverse properties such as Stripe’s merchant dashboard, consumer apps, and experiences mediated by third-party agents. You’ll be at the forefront of applied AI, solving problems for businesses and consumers, and redefining what great can look like. Responsibilities Create the home for product teams to safely build out, understand and improve their conversational experiences. Build feedback loops from conversations through improvement recommendations to generating ev

O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team: OpenAI's mission is to ensure that artificial general intelligence (AGI) benefits all of humanity. Our API is the industry's most widely adopted AI platform, empowering startups, indie developers, and Fortune 500 companies alike. Through multimodal APIs—spanning real-time interactions, text-to-speech (TTS), speech generation, and image generation—we enable users to harness the full potential of diverse AI modalities effectively and at scale. About the Role: We are seeking an Engineering Manager to lead our multimodal API product suite. Your team will be responsible for delivering innovative APIs across real-time processing, speech transcription, speech generation, and image creation. You will own the product roadmap for how we evolve our multimodal API offerings, and you will build the products that allow developers to reach millions of end users through AI audio, video, and images. In this role, you will: Build, mentor, and grow a high-performing engineering team focused on multimodal API products – including our realtime API, our transcription models (Whisper), our speech generation models (TTS), and our image generation APIs (DALLE and native 4o). Collaborate closely with product managers, designers, and other stakeholders to define the strategic vision and product roadmap. Work closely with our research teams to improve our core multimodal models for API customer use cases. Guide technical and architectural decisions, emphasizing scalability, robustness, and user experience. Foster a culture of innovation, continuous improvement, and accountability within your team. Qualifications: Proven experience managing engineering teams that deliver complex, high-quality products at scale. Strong technical background and proficiency in modern software engineering practices and system architecture. Excellent collaboration and communication skills to effectively coordinate across diverse teams and stakeholders. Familiarity with or strong interest in multimoda

AWSRestAIRust
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the role As a Pricing Strategist focused on GTM, you will help shape pricing strategy for B2B enterprise customers across our product portfolio. Working within Finance and partnering with GTM, Sales, and Product, you will focus on pricing analytics, price performance, and the effectiveness of credit programs while contributing to broader commercial strategy. In this role, you will Build regular pricing-performance reviews, analyze discounting and concessions, and turn findings into better pricing guidance. Develop commercial strategies and pricing programs for customer segments such as education, startups, and government. Define objectives and success measures for credit programs and promotions, and evaluate their return on investment. Translate segment goals and product pricing strategy into scalable pricing frameworks and commercial structures. Partner on strategic enterprise deals to align commercial proposals with sound deal economics and pricing strategy. You might thrive in this role if you Approach problems from first principles, identify root causes, and develop clear options for stakeholders. Work effectively through ambiguity and differing perspectives. Understand how sales organizations operate and collaborate well across GTM strategy, Finance, and Product. Bring relevant experience from consulting, strategy and operations, or pricing, particularly work involving analytical teams. Experience with pricing analytics, pricing frameworks, discounting guardrails, or new-product pricing is helpful, but a strictly pricing-specific background is not required. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we mu

Artificial IntelligenceAIFinance
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Our product teams work across research, engineering, product, data, and design to bring OpenAI’s technology to people and businesses around the world. Design plays a critical role in making powerful AI intuitive, useful, and trustworthy. We hold a high bar for quality and build experiences that earn users’ confidence, while moving quickly and learning from real-world feedback. We favor early validation and continuous refinement over waiting until every detail is perfect. About the Role We’re looking for a Product Design Leader to shape how startups, small businesses, and growing teams discover, adopt, and unlock lasting value from Codex and ChatGPT. You’ll lead design across the B2B growth journey, creating experiences that turn the potential of AI into meaningful, everyday impact for this user base. This role is a mix of team leadership and hands-on design execution. You’ll lead and develop a small team of designers, contribute directly to high-impact projects, and help set the standard for impactful, simple, user-centric experiences. You balance exceptional craft with momentum, creating a culture where the team launches, learns, and improves quickly. You already use tools such as Codex to extend what you can build. As a leader, you help designers strengthen their judgment, confidence, and influence through clear and actionable feedback. You’re also a highly effective cross-functional partner who brings people together, navigates ambiguity, and builds alignment through clear communication and collaborative problem-solving. Codex is on an extraordinary trajectory, and this role offers a rare opportunity to work across both sides of the product: the consumer experiences through which people first discover and adopt our technology, and the business experiences that help teams use it together. You’ll bring a high bar for craft, strong product judgment, and comfor

AWSRestAIGo
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