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Startup And Venture Ecosystem Lead in San Francisco

101 active opportunities · Updated October 2026

Explore current startup and venture ecosystem lead jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $213K/yr

Quick readStrong listing-quality and freshness signals

Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog’s Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company’s interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Support Datadog’s AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem. Attend meetups, conferences, and ecosystem events to expand Datadog’s visibility and pipeline opportunities. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog’s AI roadmap. Support negotiation processes, including term sheets and partnership structures. Collaborate on integration planning with cross-functional partners after acquisitions or strategic de

RestAIGoRust
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Corporate Development team sits at the intersection of OpenAI’s strategy and the global AI ecosystem. Partnering closely with engineering, product, and business leaders, we analyze markets, technologies, and companies to identify opportunities that accelerate OpenAI’s mission and long-term strategy. Bringing together expertise in strategy, M&A, and integration, the team leads the end-to-end process of sourcing, evaluating, negotiating, and integrating acquisitions and other strategic transactions. About the Role The Corporate Development Deal Lead will own high-priority M&A and strategic transaction work from early evaluation through diligence, structuring, negotiation, approval, and close. This person will translate strategic priorities and market insight into actionable deal opportunities, build the business case for transactions, and drive cross-functional alignment with senior stakeholders. This is a hands-on, high-ownership role for someone who can combine strategic judgment, financial rigor, founder relationship-building, and crisp execution. The ideal candidate can lead complex transactions, partner well with executive stakeholders, and help build the AI-native systems, tools, and operating practices that allow Corp Dev to scale. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead end-to-end execution of corporate development transactions (e.g., acquisitions and strategic investments), including sourcing, diligence, valuation, structuring, negotiation, and closing. Track and interpret key trends across AI, technology, and adjacent industries, translating the competitive and startup landscape into clear, high-impact insights for OpenAI’s leadership. Proactively source acquisition and other opportunities by building deep relationships across the venture, startup, and incubator ecosystem. Partner closely wi

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -67.9%

About Us: AI needs a new infrastructure layer. We're building it at Modal. Every era of computing brought new workloads that previous infrastructure couldn't support: mainframes, databases, and the cloud. Each time, the company that rebuilt the layer underneath defined the decade. AI is no different, except it touches everything instead of one slice, and the window to build the layer underneath it is open right now. Our customers include category-defining companies like Lovable , Ramp , Cognition, DoorDash, and Suno. They rely on Modal for instant GPU access, sub-second container starts, and native storage, so it's simple to serve low-latency inference, fine-tune models, and access production-ready sandboxes at scale. We recently raised a $355M Series C at a $4.65B valuation, led by General Catalyst and Redpoint Ventures. We've crossed $300M+ ARR and grown fivefold since September. Our team includes creators of popular open-source projects (e.g., Seaborn , Luig i ), academic researchers, international olympiad medalists, and experienced engineering and product leaders with decades of experience. The Role: Modal is the cloud platform built for AI. We're used by the world's leading AI labs, startups, and researchers to run compute-intensive workloads: training runs, inference, sandboxed code execution, and more. We're hiring a Community Manager in SF to make Modal a fixture in the AI developer community. You'll bring developers together through meetups, hackathons, and events of our own, and build the kind of community that keeps showing up. You know how to rinse and repeat the process, but always with a creative bend. In this role, you will: Co-host developer meetups with partners in our ecosystem. Find the right speakers, build the relationships, and run the events together. Prior examples: High Performance Inference for Open LLMs , Voice AI Builders Night , RL with Modal and Prime Intellect , FDE Happy Hour . Sponsor hackathons that attract highly technical enginee

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

About Supabase Supabase is the open-source backend platform trusted by millions of developers to build web apps, SaaS products, and AI-native applications. Our Partnerships team works across the ecosystem - technology partners, cloud platforms, VCs, accelerators, and startup programs - to make Supabase the default backend for the next generation of companies. About the Role We're looking for a Startup Partner Enablement & Programs Manager to bring our partner ecosystem to life through enablement, events, and programs to raise awareness of Supabase's value proposition to early stage startups. You'll own the materials, playbooks, and activations that help our partners - VCs, accelerators, incubators and entrepreneurship programs - successfully promote and build with Supabase. That includes organizing Supabase's presence at partner and VC-related events, running office hours, hackathons and VIP dinners, and turning relationships into repeatable, high-impact programs. This role sits on the Partnerships team and reports to the Head of Startups, working closely with teammates across the startup program, GTM, developer relations, and marketing. Because the bulk of our events and partner activity is concentrated in San Francisco and the Bay Area, we strongly prefer candidates based there who can regularly attend and host events in person. It's a great fit for someone who loves the operational craft of enablement and programs and wants to work at the intersection of startups, venture, and developer tools. What You'll Do Build and maintain partner enablement materials - decks, one-pagers, playbooks, and activation guides - that help partners across the ecosystem promote and build with Supabase Manage the operational cadence of partner programs: collaborating on strategy, tracking activations, and keeping program logistics running smoothly across partner types Organize Supabase's presence at partner and VC-related events — demo days, founder summits, portfolio workshops, p

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made of Sales, Solutions, Support, Marketing, and Partnership professionals that work together to create valuable solutions that will help bring AI to as many users as possible. About the Role OpenAI is seeking a highly motivated and experienced VC Partnerships Manager to join our Startups Go To Market team. You will play a critical role in managing relationships with top venture capital funds and startup accelerators, with the goal of providing exceptional support to the portfolio companies of these funds. We believe that many of the most disruptive and category-defining AI applications will be created by startups. The Startup Go To Market team’s mission is to help startups harness the power of AI models to drive these advances. You will support startups across stages with resources that help them get started with OpenAI APIs and build quickly, and provide access to OpenAI teams, community, and expertise to support their growth. This role is a mixture of technical understanding, vision, partnership, and strategy. You’ll be responsible for forming and managing partnerships with top venture investors, accelerators, and other partners in the startup ecosystem, as well as working across the OpenAI organization to help startups accelerate their progress and be successful using our models. You’ll work cross-functionality with product, research, engineering, marketing, support, and solutions architecture to help customers get the most out of our models. This role is based in our San Francisco office. We use a hybrid work model

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📍 San Francisco, California, United States
✓ High-confidence listing

$135.6K – $169.5K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you’ll do As a Startups Ambassador at Brex, you’ll be the face of our brand in the startup ecosystem by building trusted relationships with top-tier VC's and high-growth founders. You’ll represent Brex in the market by hosting events, driving engagement, and creating meaningful connections that bring value to the startup community. Your main focus will be to grow Brex’s presence within key venture networks by establishing and deepening partnerships, acquiring new customers, and fostering a strong local community. Success will be measured by your ability to brin

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity Postman is a rapidly growing Series D funded startup that specializes in providing innovative developer products and solutions for both individual developers and large enterprises. Our mission is to empower developers and organizations to create, test, and manage APIs more efficiently. We are currently seeking an experienced and highly skilled Field CTO to join our team, reporting to the CTO. In this role, you will work closely with customers to understand and guide their API strategy, ensuring Postman's products and services are seamlessly integrated into their architecture. What You’ll Do Act as a trusted technical advisor to Postman customers, helping them understand and navigate their API strategies and identify opportunities for Postman's products and services to add value. Collaborate with the sales and customer success teams to provide technical guidance during the pre-sales, onboarding, and ongoing support processes. Develop and deliver customer-facing presentations, demos, and workshops to demonstrate the value of Postman's solutions and help customers optimize their API management processes. Gather custome

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -67.9%
Quick readStrong listing-quality and freshness signals

About Us: AI needs a new infrastructure layer. We're building it at Modal. Every era of computing brought new workloads that previous infrastructure couldn't support: mainframes, databases, and the cloud. Each time, the company that rebuilt the layer underneath defined the decade. AI is no different, except it touches everything instead of one slice, and the window to build the layer underneath it is open right now. Our customers include category-defining companies like Lovable , Ramp , Cognition, DoorDash, and Suno. They rely on Modal for instant GPU access, sub-second container starts, and native storage, so it's simple to serve low-latency inference, fine-tune models, and access production-ready sandboxes at scale. We recently raised a $355M Series C at a $4.65B valuation, led by General Catalyst and Redpoint Ventures. We've crossed $300M+ ARR and grown fivefold since September. Our team includes creators of popular open-source projects (e.g., Seaborn , Luig i ), academic researchers, international olympiad medalists, and experienced engineering and product leaders About the Role We're hiring the first Account Managers at Modal. You'll report to the Regional Director of Account Management and be a founding member of the team. This function does not exist yet. There is no playbook, no territory map, no established motion. You'll own a book of business from day one and build the motion at the same time — from fast-moving AI startups to large enterprise teams running critical infrastructure on Modal. This is a commercial role with a revenue target. You'll be measured on retention and expansion across your accounts. While you won't be delivering the technical recommendations and implementation, the work is technical by nature. Our customers are engineers running GPU workloads, inference, and batch jobs in production, and you need to hold your own in those conversations. The profile we're hiring is a technical account manager. You've worked at companies that are deepl

RestAIGoHR
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the Role We’re looking for a Rack Power Engineer with deep expertise in high-power conversion and distribution to design, qualify, and support power systems for AI supercomputers. You will own rack power solutions—including power shelves, AC/DC rectifiers, power supply units (PSUs), power management controllers (PMCs), and high-current distribution—from requirements and supplier development through deployment. You will also monitor fleet rack power health, lead debugging and root-cause investigations, and drive improvements into hardware, firmware, and qualification coverage. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Own rack power architecture and requirements for high-power AI supercomputing systems, including power budgets, AC input interfaces, DC distribution, redundancy, efficiency, serviceability, and integration with data center infrastructure. Drive the design and supplier development of power shelves, rectifiers, PSUs, PMCs, busbars, connectors, and protection circuits. Review electrical designs and control behavior, and evaluate performance, cost, reliability, and availability trade-offs. Define and execute component, shelf, and rack qualification plans covering load transients, current sharing, hot-swap, startup and shutdown, redundancy failover, fault protection and recovery, thermal limits, and AC disturbances and ride-through

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -86%

$135K – $200K/yr

Quick readStrong listing-quality and freshness signals

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role: The Startup Market Lead, AMER role is responsible for driving startup acquisition and ecosystem growth across North America, with a initial focus on the U.S market. Based in San Francisco, this person leads regional market development initiatives across partnerships, startup communities, events, founder engagement and localized programs, helping position Notion as the preferred workspace for startups building the future with AI. Working closely with the Head of Startups and cross-functional teams, this role combines ecosystem knowledge, relationship building and execution excellence to grow startup awareness, product adoption and top-of-funnel pipeline across the region. This role is ideal for someone who understands the U.S startup ecosystem deeply, enjoys being close to founders, partners and is excited about building scalable regional growth initiatives in fast-moving markets. This role can be based in either San Francisco or New York City. We work from our offices on Mondays, Tuesdays and Thursdays (our Anchor Days) because we do our best thinking and building together in person. We’re looking for someone who’s ex

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team The Developer Experience team at OpenAI has a singular focus: empowering developers globally. Our mission is to provide every developer and startup on the planet with the most delightful and seamless experience to integrate AI into their applications and products. We ensure developers have the tools, resources, and support they need to unlock AI’s full potential. We create inspiring demos, developer tools, sample applications, and technical content that show developers how to build with Codex and frontier models like GPT-6 Astra, GPT-Live, and GPT-Image-2.5 to create powerful agents and AI-native applications. We collaborate closely with product, engineering, research, and GTM teams to ensure the developer journey, from onboarding with Codex to first API call to production deployment, is seamless, effective, and delightful. About the Role As a Developer Experience Engineer, Cyber, you will create technical content, developer tools, and sample applications that help developers and security teams secure the software they build and depend on. You will turn OpenAI’s cybersecurity capabilities, including Codex Security, into clear, runnable examples and useful learning experiences. You will work directly with developers, security practitioners, and technical founders to understand their needs and show how AI can improve secure development and defensive security workflows. We’re looking for a hands-on engineer who combines strong software skills, creativity, developer empathy, and curiosity about cybersecurity, and who can own projects from the first prototype through release and ongoing improvement. In this role, you will: Build demos, sample applications, and developer tools that demonstrate practical ways to use Codex, OpenAI’s APIs, and Cyber products for secure software development and defensive workflows. Create tutorials, blog posts, videos, and code samples that help developers understand security findings, validate and prioritize vulnerabilities, r

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.1%

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to to ship AI products. THE ROLE Are you passionate about advancing the application of artificial intelligence? We are looking for a Software Engineer focused on ML performance to join our dynamic team. This role is ideal for someone who thrives in a fast-paced startup environment and is eager to make significant contributions to the exciting field of LLM Inference. If you are a backend engineer who thrives on making things faster and is excited about open-source ML models, we look forward to your application. EXAMPLE INITIATIVES You'll get to work on these types of projects as part of our Model Performance team: Baseten Embeddings Inference: The fastest embeddings solution available The Baseten Inference Stack Driving model performance optimization RESPONSIBILITIES Implement, refine, and productionize cutting-edge techniques (quantization, speculative decoding, kv cache reuse, chunked prefill and LoRA) for ML model inference and infrastructure. Deep dive into underlying codebases of TensorRT, PyTorch, TensorRT-LLM, vllm, sglang, CUDA, and other libraries to debug ML performance issues. Apply and scale optimization techniques across a wide range of ML models, particularly large language models. Collaborate with a diverse team to design and implement innovative solutions. Own projects from idea to production. REQUIREMENTS Bachelor's, Master's, or Ph.D. degree in Computer Science, Engineering, Mathematics, or related field. Experience with one

PythonDockerKubernetesRest
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📍 San Francisco, California, United States
✓ High-confidence listingCompany trend +212.5%
Quick readStrong listing-quality and freshness signals

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Vice President, Software Engineering Overview Decision Stream is Mastercard's next-generation AI-native decisioning platform, designed to power intelligent, real-time decisions across fraud, authentication, payments, and risk. Built with a startup mindset and enterprise-scale ambition, the platform combines innovation, speed, and engineering excellence to redefine decisioning across Mastercard's global ecosystem. We are seeking a visionary and hands-on VP of Software Engineering to help build and scale the platform. This leader will partner closely with Product, Architecture, AI, and Platform Engineering teams to drive technology strategy, architecture, engineering execution, and organizational growth. What You'll Do Lead Through Technical Excellence • Serve as a senior technology leader and role model for engineering teams. • Drive architecture, design, and technology decisions across distributed systems, streaming, AI, and cloud-native platforms. • Engage deeply with engineers, architects, and product leaders to solve complex technical challenges. • Influence engineering standards, software quality, and operational excellence. Build and Scale the Platform • Help shape and deliver a highly scalable, resilient, and secure decisioning platform operating at Mastercard scale. • Balan

KubernetesAIRecruitment
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -72.4%

About Sentry Software runs the world and the pace is faster than ever. Sentry helps developers fix errors and performance issues before users notice, so teams can spend less time firefighting and more time building. Trusted by 200,000+ organizations, Sentry is today’s application monitoring standard and our team is building its AI-native future. About the Role Sentry already has a startup program: credits, partner deals with YC and a16z, a landing page with a terminal theme that developers actually think is cool. What we don't have is someone whose full-time job is making this program a real growth engine. That's this role. You'll own startup marketing end-to-end: the partner ecosystem, the community presence, the acquisition programs, the brand in rooms full of founders and early engineers. You'll take what exists today and turn it into something that makes Sentry the default monitoring choice for every new company shipping code. This role reports to the Head of Enterprise Marketing (yes, we get how this can be confusing, but she’s pretty cool) and works across Growth, Product Marketing, and DevEx. You'll have real autonomy to shape the strategy and build programs from scratch – but you'll also need to execute quickly, (kind of – we can explain more) measure what works, and kill what doesn't. In this role you will Build and scale startup partnerships. Expand relationships with accelerators, incubators, VC platforms, and startup deal aggregators. Make Sentry's credits program a no-brainer inclusion in every startup perks stack. Own the startup acquisition funnel. Design programs that move early-stage companies from free plan → credits program → paid customers → expansion. Instrument everything so we know where the pipeline is and where it leaks. Be Sentry's face in the startup ecosystem. Show up at demo days, founder events, and SF tech week. Build relationships with the people building the next generation of companies. Not because it's a line item, but because you'

B
📍 San Francisco, California, United States
✓ High-confidence listing

$181K – $226K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex The GTM team is the driving factor behind revenue for Brex and every member of our team directly affects our bottom line. We focus on generating new opportunities, acquiring new customers, and building even stronger relationships with our current customers. Our winning culture recognizes big team wins and celebrates individual accomplishments. We ensure that top performers are recognized and have built a competitive environment to motivate and unify the team. What you’ll do As a Relationship Manager for our Startups team, you play a pivotal role in the success and satisfaction of our existing Startup clients by providing the necessary resources, guidance and support. This role requires excellent communication and interpersonal skills, a deep knowledge of Brex products, an understanding of the startup ecosystem and a passion for helping entrepreneurs and finance leaders achieve their goals. Where you'll work This role wil

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