This is an exciting opportunity to participate in advancing Natera’s oncology product portfolio of cutting-edge diagnostic tests. As Manager of Statistical Programming, you will leverage your strong R programming skills and clinical trials background to contribute to the analysis and reporting of clinical trials supporting multiple regulatory submissions. Primary Responsibilities: Lead and oversee statistical programming deliverables, including ADS (Analysis Datasets) and TLF (Table, Listings and Figures), ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11. May manage a team of statistical programmers, taking responsibility for their technical and professional development, while contributing hands-on to programming work. Act as primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards. Maintain programming infrastructure, including R package development, validation, and maintenance in a controlled environment. Develop R Shiny dashboards that support data review, study monitoring, and exploration of analysis results. Promote statistical programming development and validation best practices. Work cross-functionally with Biostats, Data Management, Clinical Science, and other functions as necessary. Qualifications: Bachelor’s in Statistics, Mathematics, Computer Science, or a related field. 5+ years of related experience, with at least 3 years of experience in Clinical Trial analysis. At least 3 years of R programming experience, including package development. Knowledge, Skills, and Abilities: Proficient in R programming, including building and maintaining packages. Experience in analysis dataset and TLF generation. Prior experience in NGS, genetics, and/or oncology diagnostics preferred. Experience maintaining statistical computing environments a plus. The pay range is listed and actual compensation packages are based on a wide array of factors uniq
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Job Title: Principal Software Engineer Location: South San Francisco, CA preferred; Remote optional Job Type: Full-time About the Role We're seeking a Principal Software Engineer to join Natera's R&D team. We build the cloud infrastructure, workflow platforms, and data platforms that R&D uses to do its science - including a Kubernetes-based workflow execution platform, a custom R&D LIMS system, and a set of supporting tools that routinely handle production-scale workloads. This is a senior technical role. You'll own the full architecture, implementation, and delivery of large projects across our platform. You'll partner with the team lead on roadmap and tough technical calls, mentor mid-level engineers, and help the team find the right solution for the problem - not the most elaborate one. We're a small team (4 engineers + lead) with broad scope, and we're heavily AI-augmented: every engineer uses Claude Code / Cursor as a daily tool, and we build our own AI tooling (custom plugins, MCP servers, agents) to multiply ourselves. Responsibilities Architecture & Delivery: Own the design, implementation, and delivery of major initiatives across our platform. Take fuzzy problems through to shipped, working software used in production. Technical Leadership: Lead architecture and design reviews. Help the team find the right solution for the problem and avoid unnecessary complexity. Influence technical decisions across the team. Mentorship: Mentor mid-level engineers through code review, design docs, and pairing. Raise the engineering bar by example. AI-Native Development: Build and improve our AI-coding tooling alongside the rest of the team. Help us push the frontier of agent-driven software development inside the company. Cross-Functional Partnership: Work with bioinformaticians, scientists, and other R&D engineers to understand their needs and translate them into platform capabilities. Partner with the team lead on roadmap, prioritization, and tough te
About Graphcore Graphcore is a global leader in artificial intelligence computing systems. We design advanced semiconductors and data center hardware that provide the specialized processing power needed to advance AI while improving the efficiency required for broad adoption. As part of SoftBank Group, Graphcore belongs to a family of companies developing transformative technologies. Our AI Engineering Campus in Austin plays an important role in building the hardware platforms that support the next generation of AI systems. The Opportunity We are looking for a recent graduate or early-career engineer to join the Mech/Thermal Platform team as a Graduate Mechanical Engineer. You will contribute to the mechanical design, thermal validation, and verification of advanced AI hardware and data center systems. You will work with experienced mechanical, thermal, hardware, and systems engineers throughout the development lifecycle. The role combines 3D computer-aided design, prototype evaluation, lab testing, data analysis, troubleshooting, and clear engineering documentation. What You Will Do Create and update mechanical parts, assemblies, and drawings using Creo or comparable 3D CAD software. Take ownership of defined mechanical design tasks from requirements and concepts through detailed design, review, release, and verification. Apply mechanical design, materials, manufacturing, heat transfer, and thermodynamics principles to engineering decisions. Develop mechanical and thermal test plans and procedures for prototypes and development systems. Set up and operate laboratory equipment, collect accurate data, analyze results, and document conclusions. Evaluate prototypes and identify mechanical, thermal, assembly, or manufacturability issues. Support design verification, troubleshooting, root-cause analysis, and implementation of verified design improvements. Maintain accurate engineering documentation, including design notes, drawings, test procedures, results, and change r
Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. The Role Auth0 is seeking an entrepreneurial leader to drive the commercial and go-to-market (GTM) success of our upmarket vertical motion. Operating in a strategic partnership model alongside the Chief Product Architect you will be the commercial engine bridging our product capabilities with specialized market needs. Sitting within the Auth0 Product organization, reporting to the CPO, you will be responsible for defining our vertical market strategy, and ensuring these solutions land successfully in the market. You will partner across Okta to shape everything from customer segmentation, pricing, and packaging to field enablement and strategic partnerships. As a 0 to 1 builder, you will act as a highly leveraged executive with the opportunity to expand this mandate across multiple verticals. Key Responsibilities Vertical Strategy & Commercialization: Devise the end-to-end go-to-market strategy for our upmarket motion, driving customer segmentation, targeting, and the commercial structure (pricing, packaging, and positioning) of vertical-specific offerings. Cross-Functional Orchestration: Partner deeply with Marketing, Product Marketing (PMM), and the field to develop robust enablement programs that support Sales, Professional Services, Support and Channel Partners to successfully position and deploy Auth0 in support of up-market vertical expansion. Product Alignment: Act as the voice of the market, translating deep vertical insights and business r
Work Flexibility: Hybrid Stryker is seeking a Senior Product Safety Engineer who is passionate about developing safe, high-quality medical devices, enjoys solving technical problems while collaborating with cross-functional teams. This role offers an opportunity to build expertise in product safety during medical device development. What You Will Do: Work with Research and Development (R&D) teams to define and implement a product safety program plans for large, complex development programs for the Product Engineering business unit within Stryker Instruments. Creates product safety test plans and ensures that the plans can be completed and meet the needs of 3rd party certifier’s requirements with respect to our internal product safety testing. Apply advanced circuit and electrical system test methods Conduct or design prototyping and bench testing Conduct problem solving, identify potential solutions, and evaluate them against component and sub-system requirements Conduct research and studies to support product design Translate design inputs to engineering specifications and produce component and sub-system level designs Independently create or refine engineering documentation, such as the Design History file What You Need (Required Qualifications): Bachelor's degree in EE or related discipline and 2+ years of work experience Preferred Qualifications (Strongly Desired): Working knowledge of electrical design process, electrical components, and manufacturing methods Ability to interpret, analyze, and test electrical designs Proficiency with design and concept generation CAD, CAE, or simulation tools Ability to apply analysis tools and statistical methods Knowledge of system components a
Autism Assessor (Children & Young People) Location: Hybrid - Primarily East London (face-to-face assessments and therapy, remote follow-ups and meetings) Contract: Permanent Hours: Full-time, flexible across weekdays (flexibility around childcare and personal commitments) Our client is seeking an experienced and compassionate Autism Assessor to join their growing neurodevelopmental team. This is an exciting opportunity to work within a specialist service providing high-quality autism assessments and emotional wellbeing support for children, young people and their families. Working within a multidisciplinary team, you will deliver autism assessments, contribute to diagnostic decision-making and help shape a developing service that puts children, families and clinicians at the heart of everything they do. Key Responsibilities: Conduct comprehensive autism assessments for children and young people in line with NICE guidance and best practice. Complete structured developmental interviews with parents and carers using tools such as ADI-R Deliver observational and play-based assessments, including ADOS-2 where trained. Participate in multidisciplinary team discussions and diagnostic decision-making. Gather and evaluate information from schools, families and other professionals. Produce high-quality, child-centred clinical reports outlining strengths, needs and diagnostic outcomes. Provide clear and sensitive feedback to children, young people and their families. Maintain accurate clinical records and documentation in line with professional standards. Participate in supervision, reflective practice and team development meetings. Support service development across autism, Right to Choose, trauma-informed and educational pathways. Requirements: Professional registration with one of the following: HCPC Registered Occupational Therapist HCPC Registered Speech and Language Therapist Minimum two years' experience conducting autism assessments for children and young pe
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Elastic, the Search AI Company, enables everyone to find the answers they need in real time, using all their data, at scale — unleashing the potential of businesses and people. The Elastic Search AI Platform, used by more than 50% of the Fortune 500, brings together the precision of search and the intelligence of AI to enable everyone to accelerate the results that matter. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI. What is The Role We're looking for a Senior Software Engineer to join the Elasticsearch - Storage Engine team . This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. This role is responsible for designing, implementing, and optimizing Elasticsearch's core storage and query engine. The ideal candidate has experience building high-performance, scalable database, search, or distributed systems, with a strong focus on storage, indexing, query execution, and performance optimization. Our company is distributed by intention. We hire the best engineers we can find wherever they are, whoever they are. We collaborate across continents every day over email, GitHub, Zoom, and Slack. At our best, we write fast, scalable, intuitive and high-quality software. We believe that the best way to do that is to empower individual engineers, code review every change, decide big things by consensus, and strive for incremental improvements. What You Will Be Doing Lead the architectural evolution of core storage engine components, continuously identifying and resolving performance bottlenecks in indexing layouts, serialization formats, and r
Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. We are part of Micron’s Compute and Memory Business Unit (CMBU), where we shape how memory powers the world’s most demanding computing platforms. Our team works at the intersection of advanced DRAM technology, system architecture, and emerging AI workloads. We collaborate closely with customers, partners, and internal R&D teams to influence the future of memory-centric system design—and we have a lot of fun doing it! As a Product Architecture Engineer for DRAM, you will play a key role in defining how Micron memory technologies enable AI training and inference platforms. This role blends deep technical exploration with industry engagement and internal collaboration. You will help translate system-level challenges into differentiated DRAM solutions while influencing both customer designs and Micron’s product roadmap. Responsibilities : Explore and evaluate system architectures using modeling, simulation, and prototyping tools Engage customers and partners to identify system bottlenecks and future memory innovations Pathfind AI-focused architectures using LPDDR and DDR DRAM technologies Define and explore DRAM features that increase value in AI and high-performance systems Mentor and coach junior architects and engineers Minimum Qualifications : Bachelor’s degree in Electrical Engineering or equivalent practical experience 10+ years of experience in product engineering or product archit
Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team The Business Value Consulting and Proposals team supports long-term growth and value creation for Stripe’s largest and most strategic users. We translate Stripe's technical capabilities into measurable business outcomes and create value-led proposals that help secure and expand relationships with leading organizations. What you’ll do As a Proposal Lead, you’ll manage requests for proposals and requests for information (RFPs and RFIs) for Stripe’s largest pursuits. You’ll develop proposal strategy and narratives, coordinate contributors across Stripe, and deliver high-quality submissions that address customer requirements. You’ll also improve the processes, templates, and tools that help Stripe manage proposals consistently and at scale. You’ll bring structure to complex pursuits, build trusted relationships, and communicate clearly with contributors and leaders. This role is a good fit for someone who can balance strategic thinking with detailed execution while managing multiple deadlines and priorities. Responsibilities Lead the end-to-end bid management process, including reviewing bid invitations, supporting bid or no-bid analysis, defining the response strategy, and establishing timelines Translate customers’ business and technical requirements into clear, persuasive proposals that communicate Stripe’s value and competitive advantages Develop proposal content, including executive summaries, value propositions, and recommendations r
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