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Senior Applied Research Scientist Jobs

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Explore current senior applied research scientist jobs. Use filters to narrow by work mode, employment type, experience and date posted.

N
11 days ago

Natera’s Research team is building tests that can detect many cancers from a single blood draw. We are looking for a Senior or Lead Bioinformatics Scientist to join the team building the technology at the heart of that effort. You will work with large-scale, multi-modal genomic datasets from clinical cohorts and partner closely with molecular biologists and clinical scientists. You will help advance the state-of-the-art and drive new methods from prototype, through scalable implementation, toward clinical validation and, ultimately, to patients. PRIMARY RESPONSIBILITIES: Develop and validate new algorithms to analyze large multimodal epigenomic datasets Drive research analyses through implementation, testing and performance evaluation, including developing new features within existing pipelines Work with sequencing and clinical data from large cohorts, ensuring data integrity and quality control Partner with molecular biologists and clinical scientists to solve challenging, open-ended problems Visualize results and present complex findings to both technical and non-technical audiences Contribute to the team’s standards for code quality and reproducibility QUALIFICATIONS: Ph.D. in Bioinformatics, Computer Science, Biology, or a related field; alternatively a Bachelor’s or Master’s degree with at least 4 years of professional experience Track record developing and validating analysis workflows for high-throughput sequencing data Experience applying and evaluating statistical and ML methods to large datasets Strong quantitative reasoning and data analysis skills, applied effectively to real scientific problems. Software development experience, including proficiency in Python and its scientific computing ecosystem Fluent using Linux command-line tools and cloud computing environments Strong verbal and written communication skills Preferred Experience Working knowledge of DNA methylation and other epigenomic data Experience with cell-free DNA and liquid biopsy samp

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About Bluevine Bluevine is the largest small business banking platform in the U.S., redefining how entrepreneurs manage their money. We create modern financial solutions, from checking and lending to payments and beyond, designed to help small business owners grow, thrive, and take control of their financial future. Our best-in-class technology, advanced security, and deep understanding of the small business community give our customers the confidence to focus on what they do best. Since 2013, we’ve supported more than 750,000 small businesses nationwide. Backed by leading investors like Lightspeed Venture Partners, Menlo Ventures, 83North, and Citi Ventures, our 500+ person global team shares one mission: to give small businesses the financial tools they need to succeed. We’re innovators driven by big ideas, collaboration, and real impact. Here, you’ll have the freedom to take ownership, grow your career, and make a difference for small business owners across America. Ready to shape what’s next? This is a hybrid role . At Bluevine, we pride ourselves on our collaborative culture, which we believe is best maintained through in-person interactions and a vibrant office environment. All of our offices have reopened in accordance with local guidelines, and are following a hybrid model. In-office days will be determined by location and discipline. Key Responsibilities: Generative AI Research: Explore and evaluate Large Language Models (LLMs) and emerging generative AI techniques to identify impactful applications in data science. Model Fine-Tuning & Adaptation: Design and execute experiments to fine-tune or customize foundational models using domain-specific and internal datasets. Applied Generative AI Solutions: Leverage generative AI to enhance traditional machine learning use cases such as risk modeling, fraud detection, and customer analytics. Prompt Engineering & Evaluation: Develop effective prompting strategies and build robust evaluation and benchma

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TA
Together AI
📍 San Francisco• $165K – $210K/yr
4mo ago

About the Role Together AI is building the AI Native Cloud — an end-to-end platform for generative AI lifecycle, integrating fast, reliable inference, and model-shaping services with cutting-edge AI cloud infrastructure. We are looking for a seasoned Senior Technical Recruiter to partner closely with AI Research and Engineering leadership to scale world-class research teams across kernels, inference optimization, applied AI and model shaping. This role is ideal for someone who understands the unique dynamics of recruiting top-tier AI researchers and research engineers in a highly competitive market and can operate as a strategic talent partner to technical leadership. Responsibilities Partner with executives, research leadership, and hiring managers to define and execute hiring strategies Lead full-cycle recruiting for specialized AI talent, including researchers, research engineers, applied scientists, and ML systems engineers Build and nurture relationships with top AI talent across academia, open-source communities, research labs, and industry networks Drive exceptional candidate experiences from initial engagement through offer close, with a strong focus on relationship building and long-term talent cultivation Provide market intelligence on AI talent trends, compensation, competitive hiring landscapes, and emerging research organizations to influence hiring strategy and organizational planning Collaborate cross-functionally with sourcing, coordination, people operations, and leadership teams to continuously improve recruiting processes and operational excellence Design and refine interview processes tailored for research hiring, including technical evaluations, publication reviews, and research presentation loops Requirements 5+ years of technical recruiting experience at high-growth technology companies, with a proven track record hiring exceptional AI researchers, research engineers, applied scientists, or ML infrastructure talent at leading AI labs, hyper-sc

aisalesforce
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CH
29 days ago

Opportunity Overview: As the Sr. Manager, Applied Science, you will play a key role in building and scaling Cohere Health's AI capabilities. You'll lead a team of Applied Scientists focused on developing, evaluating, and deploying models that automate and augment complex clinical and administrative workflows. This team is responsible for the full lifecycle of applied machine learning from problem framing, rigorous attention to methods and experimentation, to partnering with AI Engineering to deploy and monitor models. You'll work with structured and unstructured healthcare data to generate insights and power intelligent systems that improve prior authorization and broader clinical decision-making. As a player-coach, you'll combine hands-on technical contributions with team leadership, helping to establish best practices, mentor team members, and drive high-impact solutions in close partnership with Product, Engineering, Clinical, and Analytics stakeholders. This is an opportunity to shape both the technical direction and team culture within a growing global organization. This is a remote-first role that may require travel to Boston, MA for new hire onboarding and occasional in-person team meetings and company events. What you'll do: Lead, mentor, and develop a team of Applied Scientists, fostering a collaborative, high-performance environment Translate complex healthcare business and clinical problems into scalable machine learning and data science solutions Validate those solutions with methodological and statistical rigor to assure that our Clinical AI is reliable, reproducible, and safe Partner with AI Engineering to scale those solutions to create real healthcare impact! Partner cross-functionally with Clinical Operations, Product, Engineering, and platform teams to align technical research and validation work with business priorities Communicate technical concepts, methodologies, and insights clearly to both technical and non-technical stakeholders Contri

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DC
Diligent Corporation
📍 Vancouver• C$151K – C$189K/yr
15 days ago

Position Overview As a Senior Staff Software Engineer on Diligent's Platform AI team, based out of our technical center of excellence in Vancouver, you will drive the architecture and technical direction of the services that bring AI research and models into production across Diligent's global product suite. You will partner with AI researchers, product managers, and Staff Engineers as peers — leading through influence across the Platform AI organization rather than through reporting authority, on secure, scalable AWS Serverless solutions that translate ML and LLM research into commercial-quality, production systems. Key Responsibilities Drive technical direction and architecture for ML/LLM systems across multiple AI platform teams, partnering with Staff Engineers rather than managing ICs in isolation. Design secure, scalable, fault-tolerant AI/ML solutions using AWS Serverless technology — event-driven, highly observable, with infrastructure as code. Evaluate and prototype new AI technologies (LLM frameworks, model providers, agentic tooling) to guide build-vs-buy decisions across the organization. Serve as the go-to contact for architecture problems and questions across the Platform AI org, and regularly present and guide architecture discussions department-wide. Mentor Staff Software Engineers and Applied Scientists through constructive code review and design partnership. Collaborate with Applied Scientists and Product teams to productize AI capabilities, translating multi-quarter AI strategy into execution roadmaps and representing engineering's perspective to senior leadership. Design, build, and scale search and retrieval systems — including OpenSearch and semantic/vector search — that power discovery, retrieval-augmented generation, and other AI-driven product features. Lead through ambiguity, helping teams navigate undefined problems to successful delivery. Required Experience/Skills 10-15+ years of professional experience developing and owning high-scale, s

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P
4mo ago

A Career with point72’s Surveillance team Point72’s Surveillance team sets the industry standard for intelligence-driven surveillance by proactively identifying, monitoring, and assessing various sources of compliance risk using proprietary tools and specialized tradecraft. We support senior management by providing strategic assessments, actionable recommendations, and real-time escalations. At Point72, members of the Surveillance team conduct integrated trade and communication surveillance and collaborate to turn information into intelligence for our internal customers. The team also monitors employee activity for evidence of violations of applicable federal securities laws, internal compliance policies and procedures, and relevant rules and regulations enforced by the SEC, FINRA, and other organizations. What you’ll do As a Machine Learning Engineer - Applied Scientist you will play a critical role in developing algorithmic solutions and models for production-ready applications that support our front office investment professionals. You will specialize in natural language processing (NLP) solutions that extract insights from unstructured text data, with additional capabilities in predictive modeling, clustering, and time series analysis. You will manage all aspects of the research process including methodology selection, data collection and analysis, implementation and testing, prototyping, and performance evaluation. You will apply, adapt, and extend existing results in the broad field of NLP, while also conducting novel research as required. Specifically, you will: Contribute to projects across various machine learning (ML) disciplines, including NLP, unstructured data analysis, predictive modeling, and classic machine learning. Implement GenAI solutions, utilize ML infrastructure, and contribute to modeling, data preparation, optimization, and performance enhancements. Work with sparse data and apply techniques to improve model accuracy and generali

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WPP
📍 Copenhagen• Full-time
2mo ago

WPP is the trusted growth partner for the world’s leading brands. We unite cutting-edge media intelligence and data solutions, world-class creativity, next-generation production, transformative enterprise solutions and expert strategic counsel in a single company – powered by exceptional talent and our agentic marketing platform, WPP Open, to help our clients navigate change, capture opportunity and deliver transformational growth. We work with the world's most valuable brands and have global reach across 100+ markets, with deep local expertise. Our people are the key to our success. We're committed to fostering a culture of creativity, belonging and continuous learning, attracting and developing the brightest talent, and providing exciting career opportunities that help our people grow. For more information, visit WPP.com. About Open Intelligence: Open Intelligence (OI) is one of WPP’s most strategic bets — a data and AI initiative at the intersection of machine learning, advertising technology, and audience insight, built to power the next generation of media intelligence. OI operates at real scale, running across the US and UK and expanding rapidly across EMEA and APAC. Our Copenhagen team has ~50 people, including 14+ data scientists and a strong engineering group. We’re flat, high-trust and fast-moving: strong opinions loosely held, teamwork over ego, aim high and have fun. Why we're hiring: Open Intelligence is accelerating the development of its core AI capabilities, and we are strengthening our applied-AI and engineering group in Copenhagen. We need a Senior Engineer who can bridge the gap between AI experimentation and production software engineering — taking cutting-edge model research, multimodal embeddings, and agentic tools, and turning them into scalable, robust, and well-architected components that power products across WPP globally. We are looking for a Senior Engineer who cares about architecture and cod

pythongcpmachine learning
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C
9mo ago

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why This Role Is Different This is not a typical “Applied Scientist” or “ML Engineer” role. As a Member of Technical Staff, Applied ML, you will: Work directly with enterprise customers on problems that push LLMs to their limits. You’ll rapidly understand customer domains, design custom LLM solutions, and deliver production-ready models that solve high-value, real-world problems. Train and customize frontier models — not just use APIs. You’ll leverage Cohere’s full stack: CPT, post-training, retrieval + agent integrations, model evaluations, and SOTA modeling techniques. Influence the capabilities of Cohere’s foundation models. Techniques, datasets, evaluations, and insights you develop for customers will directly shape the next generation of Cohere’s frontier models. Operate with an early-startup level of ownership inside a frontier-model company. This role combines the breadth of an early-stage CTO with the infrastructure and scale of a deep-learning lab. Wear multiple hats, set a high technical bar, and define what Applied ML at Cohere becomes. Few roles in the industry combine application, research, customer-facing engineeri

pythongitai
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WPP
📍 Copenhagen• Full-time
2mo ago

WPP is the trusted growth partner for the world’s leading brands. We unite cutting-edge media intelligence and data solutions, world-class creativity, next-generation production, transformative enterprise solutions and expert strategic counsel in a single company – powered by exceptional talent and our agentic marketing platform, WPP Open, to help our clients navigate change, capture opportunity and deliver transformational growth. We work with the world's most valuable brands and have global reach across 100+ markets, with deep local expertise. Our people are the key to our success. We're committed to fostering a culture of creativity, belonging and continuous learning, attracting and developing the brightest talent, and providing exciting career opportunities that help our people grow. For more information, visit WPP.com. About Open Intelligence: Open Intelligence (OI) is one of WPP’s most strategic bets — a data and AI initiative at the intersection of machine learning, advertising technology, and audience insight, built to power the next generation of media intelligence. OI operates at real scale, running across the US and UK and expanding rapidly across EMEA and APAC. Our Copenhagen team has ~50 people, including 14+ data scientists and a strong engineering group. We’re flat, high-trust and fast-moving: strong opinions loosely held, teamwork over ego, aim high and have fun. Why we're hiring: Open Intelligence is accelerating the development of its core AI capabilities, and we are strengthening our applied-AI and engineering group in Copenhagen. We need a Data Engineer who can help bridge the gap between AI experimentation and production software engineering — working alongside data scientists and senior engineers to turn cutting-edge model research, multimodal embeddings, and agentic tools into scalable, robust, and well-architected components that power products across WPP globally. We are looking for a Data

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Natera
📍 South San Francisco• $108.8K – $136K/yr
1mo ago

Scientist R&D We are seeking an innovative Scientist to join Natera's Platform Technologies team within the Research & Development organization. In this impactful role, you will conduct pre-product research to develop and advance cutting-edge NGS technologies and expand Natera's growing technology portfolio by planning, designing, and executing laboratory research. Additionally, you will investigate the feasibility of applying a wide variety of scientific principles and concepts to potential products and problems, based on your broad knowledge of state-of-the-art principles and theories. The ideal candidate will have a strong foundation in molecular biology, demonstrated experience in developing Next Generation Sequencing (NGS) technologies, and the ability to work independently with minimal supervision. Primary Responsibilities: Contributes substantially and intellectually to research and development Leads research projects to design and demonstrate the feasibility of novel nucleic acid based diagnostic methods Independently develops plans, generates ideas, and advances research objectives with minimal oversight Plans and executes complex laboratory experiments, analyzes data, and applies insights to guide and refine project direction Defines project plans with stakeholder input and coordinates efforts to achieve milestones within established timelines Coordinates the execution and analysis of effective experiments with statistics and bioinformatics teams Proposes, investigates, and implements innovative solutions to advance research objectives and overcome technical challenges Communicates progress directly with colleagues and senior management, providing regular updates on project outcomes and next steps Minimum Qualifications: Ph.D. or equivalent in molecular biology, genomics, or a closely related discipline Minimum 2 years of industry experience post-Ph.D., or at least 1 year of industry experience following the completion of postdoctoral

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We anticipate the application window for this opening will close on - 26 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life At Medtronic Neuroscience, we bring innovation, expertise, and purpose together to improve outcomes and transform lives for people living with neurological, spine, and chronic pain conditions. At Medtronic CST, we bring together innovative technologies that empower surgeons and improve outcomes in complex spine and cranial procedures. Check us out on LinkedIn: Medtronic CST . This role supports the research and development of next-generation electromagnetic navigation technologies and other strategic programs. The team applies electromagnetic theory, physics-based modeling, sensing technologies, signal processing, and system-level design to improve the accuracy, reliability, and performance of navigation solutions used in clinical applications. The position works closely with cross-functional engineering teams from concept development through prototype validation and transfer into product development. The Senior Principal Scientist will apply electromagnetic theory, system modeling, and engine

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Leidos
📍 San Diego• $87.1K – $157.5K/yr
28 days ago

Ignite your curiosity. Solve the unsolvable. At Leidos, we do more than write code—we decode the unknown. Our San Diego-based research and engineering team takes on some of the nation’s toughest defense challenges using advanced signal processing, ocean remote sensing, and high-performance computing. We’re seeking a Software Engineer / Computer Scientist who enjoys solving complex problems and pushing the limits of performance. In this role, you’ll work alongside a multidisciplinary team of scientists and engineers with expertise in hydrodynamics, physics, acoustics, and signal processing to build impactful software that turns massive, complex data sets into meaningful insight. If you are motivated by innovation, energized by collaboration, and excited to see your work support real-world missions, this could be the right opportunity for you. What You’ll Do Collaborate with scientists and engineers to design, develop, and optimize advanced algorithms for next-generation radar, optical, and infrared sensor systems. Build scalable, high-performance backend systems for scientific computing in distributed environments. Integrate, refactor, and improve scientific codebases to increase efficiency and scalability. Translate and optimize existing code for GPU/CUDA acceleration and parallel or distributed execution. Test, document, maintain, and enhance complex software in Linux/Unix environments. Contribute in a collaborative environment that values technical excellence, creativity, and continuous growth. Required Qualifications Bachelor’s degree in Computer Science, Applied Mathematics, Physics, or a related field with 4+ years of backend software development experience, or a Master’s degree with 2+ years of experience. Equivalent experience may be considered in place of a degree. U.S. citizenship and the ability to obtain a Top Secret clearance; active Top Secret clea

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G
5 days ago

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Director, Applied AI Solutions, leads the applied AI function within the AI Research Center (ARC), part of Gilead’s Clinical Data Science (CDS) organization in Drug Development. As CDS’s center of excellence for applied AI, this leader is accountable for the technical and product path from a prioritized AI use case defined by CDS functional organizations to a trusted, reusable capability in production — spanning discovery, experimentation, technical validation, first production release, adoption support, and measured value. The ownership model is deliberate. Business ownership of priorities, requirements, funding, process change, and workflow outcomes remains with the CDS and Develo

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Gilead
📍 California• $243.1K – $314.6K/yr
28 days ago

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Director, Applied AI Solutions, leads the applied AI function within the AI Research Center (ARC), part of Gilead’s Clinical Data Science (CDS) organization in Drug Development. As CDS’s center of excellence for applied AI, this leader is accountable for the technical and product path from a prioritized AI use case defined by CDS functional organizations to a trusted, reusable capability in production — spanning discovery, experimentation, technical validation, first production release, adoption support, and measured value. The ownership model is deliberate. Business ownership of priorities, requirements, funding, process change, and workflow outcomes remains with the CDS and Develo

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S
Synthesia
📍 London• Full-time• Remote
1mo ago

Synthesia is the world’s leading AI video platform for business, used by over 90% of the Fortune 100. Founded in 2017, the company is headquartered in London, with offices and teams across Europe and the US. As AI continues to shape the way we live and work, Synthesia develops products to enhance visual communication and enterprise skill development, helping people work better and stay at the center of successful organizations. Following our recent Series E funding round, where we raised $200 million, our valuation stands at $4 billion. Our total funding exceeds $530 million from premier investors including Accel, NVentures (Nvidia's VC arm), Kleiner Perkins, GV, and Evantic Capital, alongside the founders and operators of Stripe, Datadog, Miro, and Webflow. About the role As an Applied Research Engineer in our Video team, you will help build the next generation of production-grade foundation models for human-centric video generation. You will join a highly focused team working at the intersection of large-scale generative modeling, distributed systems, and production engineering. Our mission is to develop and optimize video base models that power realistic, controllable, and emotionally expressive synthetic humans at scale. This is not pure research. This is applied research with direct product impact. You will work on advancing training recipes, scaling distributed systems, improving evaluation frameworks, and optimizing inference to ensure our models are high quality, stable, and efficient enough for real-world deployment. Your work will directly influence models used by tens of thousands of businesses worldwide. What you’ll do You will own and execute end-to-end research and engineering projects, from hypothesis to production impact. This includes: Developing and scaling latent video diffusion models tailored for human-centric video generation Designing conditioning mechanisms to improve control (pose, emotion, script, camera) without sacrificing fidelity Advanc

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