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Lead Senior Manager Application Security in United States

2,565 active opportunities · Updated October 2026

Explore current lead senior manager application security jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 Tennessee, Remote, United States· Remote
✓ High-confidence listingCompany trend +237.5%

$108.6K – $250.7K/yr

Quick readStrong listing-quality and freshness signals

Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Rare Disease Sales Organization Mission & Impact Pfizer’s Rare Disease – Rare Cardiac Sales organization exists to help improve the lives of people living with serious rare cardiac conditions by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need— advancing disease and product education grounded in robust clinical evidence , promoting Pfizer Rare Cardiac therapies compliantly, and supporting healthcare professionals’ understanding of appropriate patient identification and use based on approved indications. Through evidence‑based scientific exchange, we help reduce access, diagnostic, and workflow barriers so more patients can start and stay on the right therapy. Our impact is more informed clinical decision ‑ making, improved consistency of care, and better outcomes for patients , contributing to a higher standard of care across the rare cardiac community. Role Summary The Rare Disease – Rare Cardiac, Senior Health & Science Specialist is a field-based specialty sales role responsible for driving the growth of Rare Cardiac products through compliant, strategic relationships within assigned accounts. This role partners with Therapeutic Area Specialists and Key

AIRecruitment
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📍 Tennessee, United States· Remote
✓ High-confidence listingCompany trend +237.5%

$108.6K – $250.7K/yr

Quick readStrong listing-quality and freshness signals

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Rare Disease Sales Organization Mission & Impact Pfizer’s Rare Disease – Rare Cardiac Sales organization exists to help improve the lives of people living with serious rare cardiac conditions by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need— advancing disease and product education grounded in robust clinical evidence , promoting Pfizer Rare Cardiac therapies compliantly, and supporting healthcare professionals’ understanding of appropriate patient identification and use based on approved indications. Through evidence‑based scientific exchange, we help reduce access, diagnostic, and workflow barriers so more patients can start and stay on the right therapy. Our impact is more informed clinical decision ‑ making, improved consistency of care, and better outcomes for patients , contributing to a higher standard of care across the rare cardiac community. Role Summary The Rare Disease – Rare Cardiac, Senior Health & Science Specialist is a field-based specialty sales role responsible for driving the growth of Rare Cardiac products through compliant, strategic relationships within assigned accounts. This role partn

AIRecruitment
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📍 United States· Remote
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. POSITION SUMMARY CVS Health Digital is looking for hands-on, passionate people who want to join a high energy and growing team to make a difference in customers lives and who want to be on the forefront of digital innovation that aims to reinvent what a pharmacy and a health care company can be in the digital world. Currently, we are seeking a Staff Software Development Engineer, who will serve as a senior technical leader on a cross-functional product team responsible for designing, developing, and delivering scalable healthcare technology solutions. You will play a critical role in driving architecture decisions, mentoring engineers, and partnering with product, UX, and business stakeholders to build secure, cloud-native applications that enhance the digital healthcare experience. In this role, you will lead the development of distributed systems and microservices leveraging Java, Spring Boot, event-driven architectures, and modern cloud technologies. This Staff Engineer will also guide data migration and interoperability initiatives, supporting healthcare integrations that enable seamless and secure exchange of clinical data across platforms. The ideal candidate combines strong software engineering expertise with a passion for innovation, technical leadership, and delivering high-quality solutions in an Agile environment. Expectations for the Role Software

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📍 San Jose, California, United States
✓ Quality checkedCompany trend +1233.3%

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. Our vision is to transform how the world uses information to enrich life for all. Join an inclusive team passionate about one thing: using their expertise in the relentless pursuit of innovation for customers and partners. The solutions we build help make everything from virtual reality experiences to breakthroughs in neural networks possible. We do it all while committing to integrity, sustainability, and giving back to our communities. Because doing so can fuel the very innovation we are pursuing. Job Summary The Senior Director, Semiconductor Sourcing and NPI Procurement leads the global strategy, sourcing, and supplier ecosystem for wafer foundry services, IP and EDA services, discrete actives semiconductors, and 3rd party NAND flash controller categories as well as the New Product Introduction Procurement function. This role is accountable for delivering cost competitiveness, supply assurance, and long-term resilience across a complex semiconductor value chain. Partnering closely with engineering, manufacturing, and business leaders, the role drives category strategies, supplier performance, and risk mitigation at category and product level while enabling Micron’s growth and innovation priorities. Success in this role requires deep semiconductor domain expertise, strong commercial acumen, and the ability to lead large, global teams to deliver enterprise-level outcomes. Main Responsibilities Define and execute global procurement strategies for wafer foundry services, IP and EDA ser

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 Kentucky, Remote, United States· Remote
✓ High-confidence listingCompany trend +237.5%

$108.6K – $250.7K/yr

Quick readStrong listing-quality and freshness signals

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Rare Disease Sales Organization Mission & Impact Pfizer’s Rare Disease – Rare Cardiac Sales organization exists to help improve the lives of people living with serious rare cardiac conditions by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need— advancing disease and product education grounded in robust clinical evidence , promoting Pfizer Rare Cardiac therapies compliantly, and supporting healthcare professionals’ understanding of appropriate patient identification and use based on approved indications. Through evidence‑based scientific exchange, we help reduce access, diagnostic, and workflow barriers so more patients can start and stay on the right therapy. Our impact is more informed clinical decision ‑ making, improved consistency of care, and better outcomes for patients , contributing to a higher standard of care across the rare cardiac community. Role Summary The Rare Disease – Rare Cardiac, Senior Health & Science Specialist is a field-based specialty sales role responsible for driving the growth of Rare Cardiac products through compliant, strategic relationships within assigned accounts. This role par

AIRecruitment
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📍 California, USA - Remote, United States· Remote
✓ Quality checkedCompany trend +50%

Job Requisition ID # 26WD100708 Director, Expansion & Strategic Accounts D&M We are seeking a strategic Director Expansion & Strategic Accounts to lead a regional sales organization focused on the Design and Manufacturing industry. This leader will drive revenue growth, develop high-performing teams, strengthen customer and partner relationships, and execute sales strategies aligned with Autodesk’s business objectives. What You’ll Do Lead, coach, and develop a high-performing sales team focused on revenue growth and customer expansion. Develop and execute territory and industry sales strategies aligned to Autodesk priorities. Drive quota attainment through pipeline discipline, forecasting, deal inspection, and accountability. Build strong customer, partner, and internal relationships to identify growth opportunities and deliver outcomes. Partner across sales, technical sales, customer success, partner management, marketing, finance, and product teams to improve execution. Create a culture of ownership, collaboration, inclusion, and continuous improvement. What You Bring Experience leading sales teams in enterprise software, SaaS, technology, or a related B2B environment. Track record of achieving revenue targets and building predictable sales performance. Strong understanding of territory planning, pipeline generation, forecasting, account planning, and customer expansion. Experience with direct and indirect sales channels, including partner ecosystems. Ability to lead through influence across matrixed teams and senior stakeho

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the Role As Head of Finance - Data Centers, you will be the finance leader for OpenAI’s self-built data center efforts. You will partner with teams across infrastructure, real estate, energy, construction, procurement, and finance to turn proposed sites into sound investment decisions and funded projects. This role spans the full development lifecycle: evaluating opportunities, building investment cases, forecasting capital needs, managing construction budgets, and helping determine how projects should be financed. You will give leadership a clear view of project economics, funding requirements, and risks as we build data center capacity at scale. In this role, you will: Lead financial evaluation of proposed data center and related power infrastructure projects, including site economics, development costs, capacity phasing, lifecycle costs, and key risks. Build and own project-level models and capital expenditure forecasts that connect construction schedules, power delivery, equipment procurement, contingencies, and funding needs. Establish capital budgets and financial controls for active builds. Track commitments, actual spending, change orders, and forecasts to completion; identify cost or schedule risks early. Partner with development, engineering, energy, construction, and procurement leaders on decisions that affect cost, timing, and long-term performance. Work with Treasury, Corporate Finance, Tax, and Legal to evaluate financing options, including project or construction debt, leases, joint ventures, and other partnership structures where appropriate. Prepare investment recommendations and capital approval materials for senior leadership, translating complex project details into clear choices and tradeoffs. Build a consistent portfolio view of project costs, cash requirements, milestones, and financial performance. Partner with Accounting and operations teams through project completion and handoff. You might thrive in this role if you have: Prior exper

AWSRestAIRust
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26 days ago
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the Role As a Field CTO (Strategic Pursuits) , you will serve as a strategic bridge between our customers, go-to-market (GTM) teams, and product organization. You will partner closely with Sales, Technical Success, and Product to shape high-impact deals, guide customer architecture decisions, and influence our product roadmap based on real-world adoption and feedback. This is a highly cross-functional, externally facing leadership role for someone who combines deep technical expertise with strong business acumen and customer empathy. In this role, you will: Customer & Deal Strategy Partner with Sales, Product and Technical Success teams to support complex, high-value deals as a technical and strategic advisor. Translate customer business needs into scalable technical solutions and architectures. Engage with senior customer stakeholders (CTO/CIO/VP-level) to drive alignment on vision, roadmap, and adoption. Lead technical strategy discussions during key deal stages, including discovery, solution design, and executive presentations. Architecture & Implementation Guidance Guide customers on best practices for deploying and scaling AI-driven solutions in production. Provide architectural oversight across use cases such as LLM applications, integrations, data pipelines, and security. Act as a trusted advisor to ensure long-term success, not just short-term wins. Product & Feedback Loop Bring structured customer insights back to Product and Engineering teams to inform roadmap and prioritization. Identify gaps, opportunities, and emerging patterns from customer deployments. Influence product direction based on real-world usage, scalability needs, and enterprise requirements. GTM Strategy & Thought Leadership Help shape GTM strategies by identifying repeatable patterns across industries and customer segments. Develop scalable frameworks, reference architectures, and playbooks for broader field teams. Represent the company externally through customer en

AWSRestAIGo
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📍 Washington, District of Columbia, United States· Full-time· Remote
✓ Quality checkedCompany trend -83.9%

About the Team The OpenAI for Government AI Architect team partners with public sector organizations to turn OpenAI's most capable models into meaningful, real-world impact. We work with government agencies, public institutions, and partner organizations serving the government to identify where AI can advance critical missions, design secure and scalable solutions, and help those solutions move from early exploration into sustained production adoption. The team brings together technical strategy, customer partnership, and practical deployment expertise, working closely with Sales, Product, Engineering, Research, Security, Global Affairs, and specialist delivery teams to help public sector customers adopt advanced AI responsibly and effectively. About the Role As an AI Architect, you will be the senior technical owner for a named portfolio of customers and the primary technical counterpart to their leadership teams. You will shape each customer's AI strategy and guide their journey from pre-sales discovery and solution evaluation through deployment, adoption, and measurable mission impact. You will own the technical account plan across ChatGPT Enterprise, the OpenAI API, Codex, and other agentic AI solutions. In partnership with the Account Director, you will translate mission priorities into a focused use-case portfolio, an actionable adoption roadmap, and a clear path to durable customer value. The Account Director leads the overall account strategy and relationship, while you lead the technical strategy, customer journey, and path to production impact. You will remain accountable for the technical outcome while bringing in the right specialists across deployment, implementation, enablement, security, product, and partners to provide deeper expertise and execute work where needed. This role calls for strong public sector fluency, sound architectural judgment, and the ability to move confidently between executive strategy and hands-on technical conversations. This r

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem to accelerate customer success, enable responsible enterprise AI adoption, and drive durable growth in support of OpenAI’s mission. We work cross-functionally across Sales, Solutions, Product, Engineering, Security, Legal, Finance, Marketing, Operations, and Customer Success to translate strategic partnerships into measurable outcomes for customers. Global consulting and advisory partners are essential to helping enterprises move from AI strategy to production deployment. PwC brings global reach, deep industry and functional expertise, technology and transformation capabilities, and longstanding relationships with complex and regulated enterprises. This role will lead OpenAI’s global partnership with PwC and create the strategy, operating model, and field motions needed to turn that relationship into repeatable customer and commercial impact. This role is based in San Francisco, New York City, or Seattle. We use a hybrid work model of three days in the office per week. About the Role We are hiring a Partner Director, PwC to serve as the single accountable owner of OpenAI’s strategic relationship with PwC globally. You will define the partnership thesis and joint business plan, build executive alignment, activate PwC’s industry, advisory, technology, sales, and delivery organizations, and develop repeatable go-to-market motions that accelerate enterprise AI adoption. This is a strategic and hands-on leadership role. You will move fluidly between senior executive engagement, joint account and opportunity strategy, solution and delivery alignment, field enablement, governance, and day-to-day execution. Success requires a strong understanding of how a large, matrixed professional-services organization operates, commercial discipline, technical fluency, and the ability to align teams without relying on formal authority. The ideal candidate has led a high-impact global alliance with

AWSRestAIGo
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -83.9%

About the Role OpenAI’s Applications organization spans rapidly growing Consumer, Enterprise, Developer, and Hardware businesses. As we scale across EMEA, APAC, and LATAM, we’re building the financial and operating model that will help our regional teams make faster, better decisions. We are hiring a senior Strategic Finance partner to help shape that work. You’ll serve as a trusted advisor to regional GMs, connecting market strategy with business performance and guiding where and how we invest. By bringing together insights across growth, revenue, OpEx, headcount, and marketing effectiveness, you’ll help leaders understand market health, set priorities, and drive measurable outcomes. You’ll create the frameworks, operating rhythms, and decision processes needed to scale our international business, while contributing to broader Strategic Finance priorities across Marketing. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Periodic international travel is expected. In this role, you will: Own an integrated view of OpenAI’s international performance—spanning countries, regions, and Consumer, Enterprise/API, and Developer businesses—to guide growth, resource allocation, and investment decisions. Partner with regional GMs and functional leaders to shape country strategies spanning Product, Sales, Growth and Brand Marketing, Partnerships, Communications, and Policy. Lead regional financial planning and forecasting, tracking budgets, headcount, capacity, investments, and risks against the company plan. Build and operationalize investment frameworks across markets, channels, and programs, evaluating expected returns, opportunity costs, and tradeoffs to recommend what to fund and when. Create regional and country scorecards and lead regular business reviews that track key metrics, surface risks, drive decisions, and ensure follow-through. Design decision rights and escal

SQLAWSRestAI
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📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s mission is to ensure the responsible and widespread adoption of artificial intelligence. In support of that mission, the Marketing team helps deeply understand customer audiences and market dynamics, influence the development of the right products, build sustainable and customer-aligned monetization models, and drive awareness, adoption, and usage across OpenAI’s products and platform. We take a data-driven approach to understand markets, develop monetization strategies, and uncover customer needs that shape product strategy and messaging. We partner closely with Sales, Partnerships, Product, Engineering, Research, Comms, and Design to deliver a cohesive end-to-end customer experience and lead go-to-market efforts for new product launches across channels. About the Role We’re looking for a Marketing Scientist to join OpenAI’s Ads Marketing Science function. Reporting to Marketing Science leadership, you’ll be a senior individual contributor who combines rigorous measurement expertise with strong client judgment and hands-on execution. Your mission is to help OpenAI Ads prove and improve advertisers’ media performance. You’ll work with sales, partners, and clients supporting all forms of measurement including verification, attribution, incrementality, brand, marketing mix modeling (MMM), and scalable advertiser reporting, connecting sound methodology to decisions advertisers can act on. You will partner closely with Sales on key advertising accounts and with Product, Engineering, Data Science, Partnerships, Legal, and Privacy. Initial priorities include advancing incrementality measurement, helping onboard measurement partners to privacy-forward measurement workflows and integrations, and creating reusable programs, tools, agents, skills, and workflows that let sales and clients access high-quality Marketing Science support at scale. This role is based in either San Francisco or New York, and follows a hybrid schedule (Monday-Wednesday). In th

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📍 Boise, ID - ID1, United States
✓ Quality checkedCompany trend -74.1%

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. The Site Inventory Control (SIC) team is at the forefront of our ambitious expansion efforts. SIC plays a pivotal role in connecting wafer starts, inventory strategy, cycle time management, output delivery, and factory execution. As a Senior Engineer for Fab 4 HVM SIC, you will be the operational hub, driving alignment between Technology Development (TD), High Volume Manufacturing (HVM), Probe, Supply Chain, Planning, and Engineering organizations. This outstanding opportunity allows you to lead the charge in optimizing inventory and cycle time performance while ensuring flawless factory execution! We are looking for individuals who thrive on collaboration and tackling complex operational challenges. You'll have the chance to bring to bear data to drive decisions and implement AI-enabled solutions to improve speed, accuracy, and decision-making. Responsibilities: Lead multi-functional initiatives for wafer starts, inventory, cycle time, and output performance to support business commitments Develop and improve inventory control methodologies, business processes, and operational metrics and recommend corrective actions Develop and implement inventory, priority, and capacity strategies for New Product Introduction (NPI) programs Foster coordination between Technology Development, High Volume Manufacturing, Supply Chain, Planning, and Engineering teams to optimize inventory positions and factory flow Identify and mitigate constraints, risks, and op

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📍 San Francisco, CA, United States
✓ Quality checkedCompany trend -95.8%

Employee Applicant Privacy Notice Who we are: Shape a brighter financial future with us. Together with our members, we’re changing the way people think about and interact with personal finance. We’re a next-generation financial services company and national bank using innovative, mobile-first technology to help our millions of members reach their goals. The industry is going through an unprecedented transformation, and we’re at the forefront. We’re proud to come to work every day knowing that what we do has a direct impact on people’s lives, with our core values guiding us every step of the way. Join us to invest in yourself, your career, and the financial world. The Role: Positioned in the first line of defense (1LOD) and reporting to the Head of Business Controls, this experienced executive will act as the Business Controls Lead for SoFi’s Technology and Cybersecurity organizations. This includes comprehensive coverage of Engineering, Information Security, Infrastructure, and Data across the full SoFi Legal structure: SoFi Inc., SoFi Bank, Galileo, Technisys, and SoFi Hong Kong. The Business Controls Lead will act as the direct advisor to the Chief Technology Officer (CTO), Chief Information Security Officer (CISO), and their senior leadership teams. You will lead a team of experienced IT risk & controls team charged with promoting risk awareness and ensure the overall effectiveness of risk and compliance management program implementation and execution across the 1LOD. This role provides support, advisory services, and enables strategic alignment directly to department heads to accelerate and ensure quality execution. You will be responsible for supporting and driving consistent 1LOD adherence to critical programs, such as building and maintaining risk and control self-assessments (RCSAs); identification and evaluation of control effectiveness through control testing; 1LOD risk reporting; and supporting audits and regulatory exams. You will monitor the first l

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📍 United States· Full-time
✓ Quality checkedCompany trend -100%

👋 Welcome to Glide! At Glide we’re reimagining the banking experience for the modern world . Our embedded fintech platform empowers legacy financial institutions, like community banks and credit unions, to pioneer novel digital experiences for their customers. You’ll be joining an all-star team with engineering, product, and growth experience from Stripe, Google, and Amazon. We’re looking for a talented early career Fullstack Engineer to help us build our platform. We’re bringing a new perspective to the decades-old financial world , and we’re hoping you can help us do that! Why You’ll Love This Role (Especially if you’re a new grad): A unique opportunity to work side-by-side with Glide’s founders and senior engineers, learning directly from industry veterans. Gain hands-on, end-to-end experience across the full stack: from architecture design to deployment. Be part of a small, fast-moving startup, where your code has immediate impact. Get mentorship and exposure to real-world engineering best practices, product development, and startup culture. Your Responsibilities: Move seamlessly between frontend and backend to build a well-tested, secure frontend for our core web product. Create trustworthy, safe user experiences by building interfaces that are simple, reliable, and performant using tools like Typescript, React, Node.js and NextJS . Design a scalable architecture that can serve hundreds of thousands of end users. Bring designs to life through beautifully-crafted code. Articulate a long-term technical direction and vision for maintaining and scaling our web product suite. Lead frontend and backend infrastructure & tooling for an ambitious product roadmap. Need-to-Haves: Experience with Javascript and tools like Typescript, React, Node.js and NextJS . Experience with modern, responsive HTML & CSS . Experience using data fetching libraries like React Query/Tanstack or tRPC to synchronize client and server data. Excellent understanding of software engineer

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