Jobs in United States

Lead Senior Python Engineer in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior python engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $326.1K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Principal Security Software Engineer on the Production IAM team, you will set the technical direction for how identity and access work across Roblox's production infrastructure, from the mTLS-based identity that services use to authenticate to one another, to the privileged access controls that govern how engineers reach production. The team is accountable for Roblox's machine and workload identity platform, its centralized authorization engine, its production access management platform, production PKI and certificate lifecycle, and just-in-time privileged access for engineers. As an individual contributor in Production IAM, you will define multi-year strategy, drive alignment across Roblox Platform, mentor senior and staff engineers, and personally build the hardest parts of these systems. As AI agents become first-class actors in production, you will also help pioneer how they get identity, prove who they are, and receive safely-scoped access. You will Lead the architecture for production identity and access. Define and evolve the end-to-end design for machine, workload, human, and AI-agent identity across our hybrid on-prem and cloud fleet, making secure access invisible when

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📍 United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $212K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Difference You Will Make: Airbnb is entering a new era—reimagining how fraud, safety, and quality are measured, protected, and elevated across the digital landscape. Reporting to the Director of Advanced Analytics, Fraud & Safety, you will lead a dispersed team of ~8 advanced analysts tasked with turning safety measurement into governed, self-serve decision systems for Policy, Ops, Legal, Product, and Engineering. You will be a pivotal leader safeguarding Airbnb’s global community. You’ll steer a multidisciplinary team that designs, delivers, and scales state-of-the-art analytics for: Safety (physical & digital) Connected-account & circumvention detection Privacy protection & risk management This role isn’t just about reporting what happened; it’s about building the systems that help Airbnb see around corners. You will democratize data access, build always-on scenario simulators for fraud and safety, and turn incident impacts into seamless signals for continuous improvement. Your insights and systems will empower every stakeholder—from legal to operations, policy to product—to make bold, data-driven, and context-aware decisions in real time. A Typical Day: Own end-to-end analytical workflows for platform safety controls: data ingestion, feature engineering, modeling, experimentation, and visualization. A core mandate is to co-own and drive the enterprise-wide “Safety Single Source of Truth” (SSoT) strategy —a unified, structured data asset and taxonomy that underpins decision-making across Product, Operations, Policy, and Legal. Ensure metrics are future-proof, privacy-compliant, and g

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O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team OpenAI's research training infrastructure powers how our frontier models are trained and evaluated. The Simulation team sits at the intersection between the agentic harness that powers OpenAI's products and the research infrastructure where GPT-next is trained, ensuring that our model's training environment is as realistic as possible. This team owns the integration layer that connects our production harness capabilities into the training stack. The work is highly cross-functional and high leverage: researchers depend on it to run experiments and evaluations reliably as well as to develop the next generation of harness capabilities. Failures in this surface can materially affect training velocity and correctness. About the Role We're looking for a Principal Software Engineer to lead the architecture and evolution of the Simulation Platform. You'll own a critical interface between research and engineering, building the systems, APIs, and operational patterns that let researchers use agentic coding infrastructure safely and effectively in training environments. This role is ideal for a senior backend or infrastructure engineer with strong technical judgment, product sense for highly technical users, and the ability to drive execution across multiple teams. The highest-leverage work is building robust infrastructure that supports and accelerates research without compromising engineering quality. In this role, you will Design, build, and evolve the integration between the Codex harness that powers OpenAI's products and research training infrastructure used for training GPT-next Build a platform for our LLMs to train and be evaluated in simulated environments that mimic their deployment setting as closely as possible, on every axis: agentic harness, compute substrate, timing, tools, data sources, humans in the loop, and more Own major integration surfaces end-to-end, from architecture and API design through rollout, operations, and long-term maintenance Bu

PythonAWSRestAI
TN
📍 New York, NY, United States· Remote
✓ High-confidence listing

From $140K/yr

Quick readStrong listing-quality and freshness signals

The mission of The New York Times is to seek the truth and help people understand the world. That means independent journalism is at the heart of all we do as a company. It’s why we have a world-renowned newsroom that sends journalists to report on the ground from nearly 160 countries. It’s why we focus deeply on how our readers will experience our journalism, from print to audio to a world-class digital and app destination. And it’s why our business strategy centers on making journalism so good that it’s worth paying for. About the Role New York Times Wirecutter team is looking for a Senior Manager, Audience & Product Analytics to power our growth strategy. Your core mandate will be to build an understanding of our audience— who they are, how they engage with content and product features, and what brings them back. You will lead a team of analysts responsible for understanding audience trends, driving product improvement, and optimizing user engagement. You will provide leadership and data-driven insights, working with audience, product, and engineering leads to establish goals, design experiments, and uncover new opportunities. You will report to the Executive Director of Data Analytics and Insights, Wirecutter. This opportunity is flexible to in office or remote work. Responsibilities You will manage a team of three direct reports—promoting a culture of curiosity and excellence while setting clear deliverables, supporting career growth, and ensuring high-quality analytics output You will analyze audience growth, traffic drivers, customer journey touch points, and user engagement trends to inform strategic decision-making. You will partner with functional leads (Product, Design, Engineering, Editorial) to set strategy, define goals, and build the audience and product analytics roadmap. You will lead the design, execution, and post-analysis of product experiments (A/B testing). Provide expertise on primary metrics, trade-offs between competing goal

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MT
📍 Boise, ID - Main Site, United States
✓ High-confidence listingCompany trend +1266.7%
Quick readStrong listing-quality and freshness signals

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. As a Principal Engineer at Micron’s HBM New Product Validation team in Boise, ID you will be a senior technical guide responsible for validation strategy and readiness for future-generation High Bandwidth Memory (HBM) products. You will apply deep expertise in complex RAM and high-bandwidth memory architecture and building to establish architecture validation strategies. You will impact decisions that improve validation observability and debug efficiency . You will lead investigations of complex architecture, building , and silicon issues from pre-silicon simulation through post-silicon characterization. You will partner across Design Engineering, Design Validation, Product Engineering, Systems teams, and will develop and promote AI-enabled validation methodologies that improve efficiency, quality, and scalability. Responsibilities: Define architecture-aware validation strategies and coverage direction for future-generation HBM products. Drive validation readiness for next-generation products by preparing strategies, test environments, and execution plans before first silicon, reducing risk, accelerating issue resolution, and preventing late-stage surprises. Evaluate new DRAM/HBM architectural features and define validation requirements and testability needs before DBR. <span style="color:#

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📍 United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: The Staff Data Engineer is a senior, hands-on technical contributor within an Enterprise Data domain, owning technical design and the most complex implementation work for assigned data products, capabilities, and integrations. The role establishes, communicates, and evolves the technical approach for the work it leads and is accountable for the quality, durability, and supportability of the solutions it shapes. Staff Data Engineers work directly with business stakeholders to understand needs and shape technical solutions, engaging at a level appropriate to the work they lead. The role is expected to be fluent in both technical execution and business context, translating between them without losing precision in either. The Staff Data Engineer sets technical direction for assigned capabilities and initiatives within the domain, applies enterprise standards and platform patterns, engages Principal Engineers where cross-domain considerations apply, and multiplies the effectiveness of the domain team through design leadership, code review, and mentoring. This role is based in Madison, WI . Essential Duties Include, but are not limited to, the following: Technical design and solutioning Own technical design and hands-on delivery for the most complex or highest-risk work across assigned data products, capabilities, and initiatives, including data models, pipeline architecture, integration patterns, and platform usage decisions. Produce design docume

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📍 Austin, Texas, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Staff -Power and Performance Validation Engineer About us Graphcore is one of the world’s leading innovators in Artificial Intelligence compute. It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone. Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation. Job Summary Reporting to senior leadership within Architecture and Validation, the Power and Performance Validation Lead will drive validation strategy and execution for advanced AI compute silicon and systems. The role is responsible for leading power, thermal and performance validation activities across pre-silicon and post-silicon environments to ensure products meet efficiency, reliability and scalability expectations. This role requires strong technical expertise and collaboration across multiple engineering disciplines to deliver robust validation methodologies, scalable automation frameworks and actionable performance insights. The Team The Power and Performance Validation team sits within the Architecture and Validation organisation and is responsible for validating the performance, efficiency and thermal behaviour of Graphcore silicon and systems. The team supports the full product lifecycle, from early architectural modelling through to first silicon bring-up, characterization and production readiness. Engineers work closely with cross-functional teams globally to debu

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SF
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%

From $200K/yr

Quick readStrong listing-quality and freshness signals

About Stitch Fix, Inc. Stitch Fix (NASDAQ: SFIX) Stitch Fix is redefining retail by combining human creativity with advanced data science and Generative AI. As we build the future of personalized shopping, we’re equally committed to building yours. We believe in investing in our team as much as our technology. Join us to be a trendsetter in the industry and help us redefine what’s possible for our clients, while we help you reach your full potential. About the Role At Stitch Fix, we are at the forefront of innovation, creating cutting-edge solutions that blend fashion, technology, and data science. Our data science team combines machine learning with expert human judgment to generate innovative recommendations and insights that transform the way our clients discover what they love. We believe in a curiosity-driven data science culture where members are empowered to deliver impact through end-to-end model development. The diversity of the problems that we work on and the data-rich environment of our business make it possible, even essential, to bring the tools of multiple disciplines to bear on our hardest problems. We are looking for an experienced Styling Algorithms Team Manager to lead a group of talented machine learning engineers and data scientists. In this role, you will shape the future of fashion technology by driving the development and deployment of our styling algorithms, which empower our human stylists to delight clients by nailing their fit and style. This includes ML-, AI-, and product-driven feature curation and testing for our proprietary styling platform, as well as client-facing AI personalization experiences, such as Stitch Fix Vision, our virtual try-on. Responsibilities: Champion bold AI and ML interventions to improve our styling experiences, enabling our stylists to have a multiplicative impact on their client connection points. Likewise, actively shape the product roadmap for direct client-facing styling experiences, expand

PythonRestMachine LearningAI
SF
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%

From $200K/yr

Quick readStrong listing-quality and freshness signals

About Stitch Fix, Inc. Stitch Fix (NASDAQ: SFIX) Stitch Fix is redefining retail by combining human creativity with advanced data science and Generative AI. As we build the future of personalized shopping, we’re equally committed to building yours. We believe in investing in our team as much as our technology. Join us to be a trendsetter in the industry and help us redefine what’s possible for our clients, while we help you reach your full potential. About the Role At Stitch Fix, we are at the forefront of innovation, creating cutting-edge solutions that blend fashion, technology, and data science. Our data science team combines machine learning with expert human judgment to generate innovative recommendations and insights that transform the way our clients discover what they love. We believe in a curiosity-driven data science culture where members are empowered to deliver impact through end-to-end model development. The diversity of the problems that we work on and the data-rich environment of our business make it possible, even essential, to bring the tools of multiple disciplines to bear on our hardest problems. We are looking for an experienced Styling Algorithms Team Manager to lead a group of talented machine learning engineers and data scientists. In this role, you will shape the future of fashion technology by driving the development and deployment of our styling algorithms, which empower our human stylists to delight clients by nailing their fit and style. This includes ML-, AI-, and product-driven feature curation and testing for our proprietary styling platform, as well as client-facing AI personalization experiences, such as Stitch Fix Vision, our virtual try-on. Responsibilities: Champion bold AI and ML interventions to improve our styling experiences, enabling our stylists to have a multiplicative impact on their client connection points. Likewise, actively shape the product roadmap for direct client-facing styling experiences, expand

PythonRestMachine LearningAI
SF
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%

From $200K/yr

Quick readStrong listing-quality and freshness signals

About Stitch Fix, Inc. Stitch Fix (NASDAQ: SFIX) Stitch Fix is redefining retail by combining human creativity with advanced data science and Generative AI. As we build the future of personalized shopping, we’re equally committed to building yours. We believe in investing in our team as much as our technology. Join us to be a trendsetter in the industry and help us redefine what’s possible for our clients, while we help you reach your full potential. About the Role At Stitch Fix, we are at the forefront of innovation, creating cutting-edge solutions that blend fashion, technology, and data science. Our data science team combines machine learning with expert human judgment to generate innovative recommendations and insights that transform the way our clients discover what they love. We believe in a curiosity-driven data science culture where members are empowered to deliver impact through end-to-end model development. The diversity of the problems that we work on and the data-rich environment of our business make it possible, even essential, to bring the tools of multiple disciplines to bear on our hardest problems. We are looking for an experienced Styling Algorithms Team Manager to lead a group of talented machine learning engineers and data scientists. In this role, you will shape the future of fashion technology by driving the development and deployment of our styling algorithms, which empower our human stylists to delight clients by nailing their fit and style. This includes ML-, AI-, and product-driven feature curation and testing for our proprietary styling platform, as well as client-facing AI personalization experiences, such as Stitch Fix Vision, our virtual try-on. Responsibilities: Champion bold AI and ML interventions to improve our styling experiences, enabling our stylists to have a multiplicative impact on their client connection points. Likewise, actively shape the product roadmap for direct client-facing styling experiences, expand

PythonRestMachine LearningAI
R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $226.4K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As Senior Technical Program Manager for the Human-in-the-Loop (HITL) Operations , you will own the end-to-end lifecycle of Roblox's AI data labeling and model evaluation ecosystem. This is a high-leverage, high-ownership role at the intersection of Research, Engineering, and Operations. You will scale our data operations that is handling million of items evaluated annually today with projection of 4x the current volume by 2030, managing a multi-million annual budget and a distributed workforce of 100+ remote contractors — all while driving the platform evolution from manual workflows to AI-assisted, LLM-accelerated operations. This is a rare opportunity to build the data infrastructure that directly determines the quality of Roblox's AI models across creator tools, content discovery, in-experience AI, and 3D generative content — at the exact moment when human judgment is the critical ingredient for getting these models right. You Will Lead data programs end-to-end. Own the full lifecycle of labeling and model evaluation workflows across Roblox's AI teams — from translating ambiguous ML requirements into structured annotation tasks, to overseeing contractor execution, quality review, a

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C
📍 Buffalo Grove, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Role Summary At CVS Health®, you’ll be working with a team of passionate colleagues who care deeply, innovate with purpose, hold themselves accountable and prioritize safety and quality in everything we do. Do you enjoy innovation while having fun doing it? If the answer yes, then this role might be for you! Join us and be part of something bigger, innovative and simplification in healthcare. We are seeking a highly experienced and innovative Principal (Director Level) Software Development Engineer to lead the application architecture, design, development, delivery of next-generation digital applications (including Reporting and financial solutions), and optimization of scalable, secure, and high-performance solutions leveraging AI across all major cloud platforms (AWS, Azure, and GCP). This role requires deep technical expertise, AI-enabled solutions, strategic thinking, scalable digital platforms, and enterprise integrations that power critical healthcare and pharmacy experiences and a passion for driving excellence in software engineering practices. This is a senior technical leadership role for a hands-on engineer who can operate across the full stack—from intuitive front-end applications to resilient backend services—while setting architectural direction, influencing engineering standards, and mentoring teams. The ideal candidate combines deep technical expertise, platform thin

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📍 San Francisco, United States· Full-time
✓ High-confidence listingCompany trend -98.8%

From $204K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Total Rewards Compensation team serves as a strategic advisor to business leaders, managers, and employees across Airbnb. We are compensation experts with a deep understanding of our stakeholders, problem solvers who use data and insights to drive value, and partners who build the tools, models, and frameworks that support sound compensation decision-making across the company. This role sits within the Compensation function and will work closely with the Technology organization and cross-functional partners including Talent Directors, Recruiting, People Analytics, Finance, and Legal. The Difference You Will Make: We are looking for a Senior Compensation Partner to own Airbnb's compensation strategy for the Technology organization, covering functions such as Engineering, Infrastructure, ML/AI and Data Science. You will be the primary Total Rewards advisor to Technology leadership and the compensation point of contact for Talent Directors and Recruiting, defining how Airbnb competes for AI, ML, and frontier engineering talent. Working alongside our regional Total Rewards Partners, you will hold a global view of how we pay technical talent across all markets. Beyond your client group, you will contribute to the design and strategy of complex global programs, lead core Total Rewards priorities, and build the models and tools the broader Compensation team relies on. You are equally credible advising our most senior technical leaders and in the data behind the recommendation. A Typical Day: Serve as the senior compensation advisor to Technology leadership across func

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📍 Boise, ID - ID1, United States
✓ Quality checkedCompany trend -75%

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. The Site Inventory Control (SIC) team is at the forefront of our ambitious expansion efforts. SIC plays a pivotal role in connecting wafer starts, inventory strategy, cycle time management, output delivery, and factory execution. As a Senior Engineer for Fab 4 HVM SIC, you will be the operational hub, driving alignment between Technology Development (TD), High Volume Manufacturing (HVM), Probe, Supply Chain, Planning, and Engineering organizations. This outstanding opportunity allows you to lead the charge in optimizing inventory and cycle time performance while ensuring flawless factory execution! We are looking for individuals who thrive on collaboration and tackling complex operational challenges. You'll have the chance to bring to bear data to drive decisions and implement AI-enabled solutions to improve speed, accuracy, and decision-making. Responsibilities: Lead multi-functional initiatives for wafer starts, inventory, cycle time, and output performance to support business commitments Develop and improve inventory control methodologies, business processes, and operational metrics and recommend corrective actions Develop and implement inventory, priority, and capacity strategies for New Product Introduction (NPI) programs Foster coordination between Technology Development, High Volume Manufacturing, Supply Chain, Planning, and Engineering teams to optimize inventory positions and factory flow Identify and mitigate constraints, risks, and op

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📍 United States· Full-time
✓ Quality checkedCompany trend -90%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Our Data and Analytics team is currently looking for a Senior Data Scientist to join us! You’ll be responsible for laying the foundation for a best-in-class business analytics function. You’ll partner closely with our business stakeholders to ensure that our analytics stack and processes meet the business needs today with an eye towards the future. What you’ll do as a Senior Data Scientist at Vanta: Build and maintain trusted product data assets using dbt, Snowflake, and modern analytics infrastructure Leverage AI-powered analytics tools and data agents (e.g., Snowflake Cortex) to accelerate insight generation, automate repeatable analysis, and scale decision-making Define and evolve measurement frameworks for product health, customer lifecycle, and AI-powered product experiences Partner closely with Product, Engineering, Design, and Customer Success to influence product strategy through data Help define Vanta’s analytics strategy and AI measurement practices as our product and data platform evolve Lead executive analytics reviews, translating complex analyses into clear recommendations that drive company decisions How to be successful in this role: 4+ years of experience working with data as a Data Scientist, Product Analyst, or Analytics Engineer in an applied business setting Strong foundation in SQL, Python (or R), statistics, and machine learning Experience designing and evaluating experiments, predictive models, and other statistical analyses to inform product decisions Experience building scalable data assets, metrics, and analytical frameworks on modern cloud data platforms (e.g., Snowflake, dbt) Deep experience with da

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