Jobs in United States

Senior Lead Technical Program Manager Knowledge Systems in United States

1,941 active opportunities · Updated October 2026

Explore current senior lead technical program manager knowledge systems jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-65.7%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $80K/yr

Quick readStrong listing-quality and freshness signals

The GTM Strategy & Operations Associate will join a global team driving Datadog’s next phase of growth. We’re interdisciplinary thinkers leveraging diverse business backgrounds in tech, management consulting, investment banking and business development to accelerate Datadog’s global growth. We work directly with Datadog’s most senior leaders to set corporate strategy, improve efficiency across the business, support data-driven decision-making, own complex operations, and more. In this role, you will identify opportunities for revenue growth and design strategic go-to-market (GTM) initiatives by evaluating business tradeoffs and partnering with senior leaders to shape GTM strategy. You will drive key planning processes, including capacity planning and quota planning, optimization and expansion strategies, and KPI design and measurement. Additionally, you will lead critical operational initiatives and long-term strategic projects that improve execution and help build the foundation for the company's continued growth. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What you’ll do: Strategic roadmap development: Develop short- and long-term GTM strategies by identifying growth opportunities, setting business priorities, and aligning sales and growth targets. Lead strategic planning initiatives, including headcount and KPI planning, incentive design, and cross-functional projects to improve execution and accelerate revenue growth. Global quota ownership: Own quotas for the global Sales organization – build and maintain quota models, adjust them throughout the year in response to org changes, and drive stakeholder alignment along the way. GTM analysis, reporting, and modeling: Analyze sales and GTM data to identify trends and understand efficiency by channel. Develop data

PythonSQLAIGo
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -82%
Quick readStrong listing-quality and freshness signals

About the role OpenAI is building a world-class global mobility and immigration program—agile, compliant, technology-enabled, and designed to help exceptional people work where they can have the greatest impact. In this role, you will lead high-impact strategic initiatives, including U.S. permanent residence strategy, M&A, organizational change, and global expansion. This is a senior individual-contributor role for a builder who can translate legal and operational complexity into clear, practical solutions. Reporting to the Head of Global Mobility & Immigration, you will partner with the broader team and lead through expertise and influence across Legal, Corporate Development, Recruiting, People, Finance, business teams, and external counsel to turn emerging business needs into scalable programs, policies, and durable controls. What you'll do Set the roadmap, principles, governance, and operating model for priority global mobility and immigration initiatives. Lead the U.S. permanent residence strategy, including PERM planning, controls, communications, compliance and continuous improvement. Own immigration and mobility workstreams for M&A, divestitures, restructurings, entity changes, and new-market entry—from diligence through integration. Lead global expansion strategy, ensuring work authorization, business travel, and compliance in rapidly growing international jurisdictions. Build reusable playbooks, decision frameworks, risk assessments, and change-management plans. Partner with Legal, Corporate Development, Recruiting, People, Finance, and business leaders to identify implications early and drive sound decisions. Establish dashboards and program-health measures covering compliance, cycle time, quality, cost, vendor performance, and employee experience. Manage external counsel and vendor partners through clear service levels, quality standards, budgets, and outcomes. Use systems, automation, and AI-enabled tools to improve case handling, documentati

AWSRestAgileAI
P
📍 Massachusetts, United States
✓ Quality checkedCompany trend +671.4%

$162.9K – $271.5K/yr

ROLE SUMMARY: The key strategic focus within the Internal Medicine Research Unit (IMRU) is identifying novel therapies to prevent or treat metabolic diseases such as obesity and cardiovascular disease. Our goal is to build a world-class research team of dedicated scientists committed to developing a deep mechanistic understanding of the metabolic pathways underlying disease pathogenesis. As a senior scientific leader and member of the obesity discovery biology team, this individual will play a significant role in shaping the scientific direction for the obesity therapeutic area and influencing broader IMRU research strategy and portfolio priorities. The individual will help create and drive discovery research strategy across multiple programs, including target ideation, validation, translational biomarker strategy, hypothesis testing, and early clinical development within the IMRU obesity portfolio. The successful candidate will lead through both direct team leadership and influence across multidisciplinary partners, helping align scientific decisions across discovery biology, translational sciences, clinical, computational, and external collaborators. The individual will identify emerging therapeutic opportunities, advance portfolio programs with scientific rigor and urgency, and represent research strategies to internal leadership and the external scientific community. Knowledge and experience in the study of metabolic pathways are essential, and familiarity with the pathophysiology of dysmetabolic states would be advantageous. Strong self-motivation, excellent communication and interpersonal skills, and the ability to lead, mentor, and build scientific capability in a highly collaborative environment are essential. ROLE RESPONSIBILITIES: Shape and influence the scientific direction for discovery research programs aligned with IMRU therapeutic area and portfolio strategy. Ap

AIRecruitment
S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Staff Network Engineer Location: MPK/Bellevue/Dublin Snowflake's Enterprise Technology Network Services team is looking for a Senior Network Engineer to lead the design, operation, and optimization of our Zero Trust and secure-access platform. This role is Zscaler-centric — you will own the health, performance, and roadmap of our ZIA/ZPA deployment — while working across a modern, multi-cloud network stack that supports a global workforce of 10,000+ users. You'll be the escalation point for the most complex connectivity issues and a driver of automation and observability across the environment. What You'll Do Own and operate the Zscaler platform (ZIA, ZPA, ZDX, ZCC) end-to-end, including policy frameworks, app-segmentation models, PAC/traffic-forwarding standards, App Connector topology, and NSS/log-streaming design. Troubleshoot secure-access incidents like tunnel flapping, broker/connector health, SSL inspection edge cases, DNS/DTLS failures, and lead root-cause analysis for systemic issues. Manage Palo Alto firewalls, Panorama and GlobalProtect VPN, while planning migration toward Zscaler solutions. Support Aruba (Central) Wireless, Ekahau and Cisco Catalyst switches globally. Design, install, and configure network devices and ISP circuits at new offices. Build automatio

PythonVueSQLAWS
R
📍 Foster City, California, United States· Full-time
✓ Quality checkedCompany trend -85.9%

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. Replit is changing who gets to build software. As an agentic software creation platform, Replit enables anyone, from individual creators to teams inside the world’s largest companies, to turn natural language into applications, internal tools, dashboards, workflows, websites, and software that solves real problems. We are looking for a Director or VP of Communications to help lead Replit’s next chapter of storytelling, reputation building, and market awareness. This is a senior communications role for a creative, strategic, and hands-on leader who can help build and scale the communications function as Replit grows from a beloved developer platform into a defining company in AI, software creation, and enterprise transformation. This person will help own Replit’s external and internal communications strategy, including company narrative, media relations, analyst relations, executive communications, internal communications, crisis communications, customer storytelling, policy-related communications, and global awareness. The role requires someone who can push through the noise and make the Replit story heard and for it to be a part of the narrative at all times. The Director / VP of Communications will help develop a compelling narrative that evolves with the company, the product, and the market, and deliver that narrative to the audiences across media, policymakers, partners, customers, potential ones and employees.The role will also support Replit’s international awareness, with a focus on key markets in Europe and Asia. This person must be both strategic and execution-oriented. They should have been able to build a comms function at a fast-growing technology company or have been the second in command at one. But, this

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $128K/yr

Quick readStrong listing-quality and freshness signals

We’re looking for an experienced sourcing leader to join the Datadog Procurement team and help grow the Strategic Sourcing group. Make an impact by partnering closely with senior technology and business leaders, owning our fastest-growing AI, neocloud, and inference spend end-to-end, and continuing to prove the value that Strategic Sourcing brings to the organization. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the AI spend category end-to-end, covering foundation-model and AI APIs, AI development and productivity tools, and AI-enabled SaaS (with neocloud and inference compute as an emerging area), while developing and executing category strategies aligned to business objectives Champion AI and automation adoption across the sourcing function by identifying tools (e.g. Claude, ChatGPT) and building repeatable workflows that make sourcing faster, smarter, and more scalable Lead high-value AI vendor negotiations spanning foundation-model and API agreements, AI development and productivity tools, and AI SaaS, structuring seat- and consumption-based pricing across net-new purchases and strategic renewals, and building neocloud and GPU-capacity capability as the category grows Partner with Engineering and Finance to turn architectural and consumption trade-offs into commercial business cases, forecasts, and savings targets Build pricing and consumption models and apply FinOps discipline to quantify buying scenarios and uncover savings across a fast-moving spend base Work alongside executive and senior technology leadership as a trusted advisor on AI and neocloud investment decisions, influencing strategy and commercial trade-offs at the leadership level Track category KPIs (savings, pipeline, cycle time), monitor AI market, vendor, and pricing trends,

M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $151K/yr

Quick readStrong listing-quality and freshness signals

MongoDB’s Security Product Management team is seeking a Staff Product Manager to own security, compliance, and public sector product strategy within Atlas for Government (A4G). In this role, you will be a key member of the security product management team, helping make data security a market differentiator that enables MongoDB to win in enterprise and regulated industries. You will lead product strategy and execution for capabilities and programs that support federal compliance requirements and broader regulated-industry needs. You will work across Engineering, Compliance, Legal, Security, and Go-to-Market teams to translate complex regulatory and customer requirements into clear product investments, roadmaps, and outcomes. This role is suited for a candidate who can orchestrate multiple interlinked product areas, own cross-team product and architectural trade-offs, and align senior stakeholders around multi-year bets. You will be expected to identify opportunities and dependencies that cut across team boundaries, bring clarity to ambiguous problem spaces, and establish reusable ways of working that help MongoDB deliver secure, compliant platform capabilities for public sector and other regulated markets. You will partner closely with senior engineering and business leaders to evaluate trade-offs, sequence investments, and bring clarity to decisions that balance customer impact, execution risk, and long-term business value. This role can be based out of of our offices or remotely in the United States. The Federal Risk and Authorization Management Program (FedRAMP) is a US government-wide program that provides a standardized approach to security assessment, authorization, and continuous monitoring for cloud products and services. Our FedRAMP program requires that anyone who is accessing customer data or metadata inside the Authorization Boundary be a US Person on US Soil. Responsibilities Security and Compliance Product Strategy Own the public sector compliance roadm

MongoDBAWSAzureGCP
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking a senior Actuator Electromagnetic Design Engineer to lead the development of custom electromechanical actuators for advanced robotic systems. You will own actuator development from early architecture and concept generation through prototype validation and system integration, partnering closely with mechanical, electrical, controls, firmware, reliability, and manufacturing teams. This role focuses on the design, integration, and validation of precision electromechanical systems, including motors, transmissions, sensing, structural components, and thermal architectures. You will help drive actuator development across the full engineering lifecycle while establishing scalable design, test, and integration practices for future robotic platforms. This role is based in San Francisco, CA, and requires in-person presence 4 days a week. In this role, you will: Lead the architecture, design, and integration of custom robotic actuators, including the design, simulation, integration and sourcing of custom electromagnetic components. Define actuator requirements and system-level trade studies around torque density, bandwidth, efficiency, thermal performance, inertia, reliability, manufacturability, and cost. Design precision electromechanical assemblies with strong attention to tolerances, alignment, load paths, thermal expansion, sealing, wear, and serviceability. Drive actuator integration into robotic systems, partnering closely with controls, firmware, electrical, and robotics software teams to optimize closed-loop performance. Devel

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team OpenAI’s Legal team plays a crucial role in advancing our mission by tackling novel and consequential legal issues in AI. The commercial infrastructure legal team supports the systems and facilities that make advanced AI possible, including compute, first-party silicon, colocation, and first-party data center development. About the Role We’re seeking a senior commercial infrastructure lawyer to lead legal work across our rapidly growing data center development and colocation portfolio. You will advise on complex, high-value transactions involving new data center sites, power, construction, colocation, and related infrastructure arrangements. This role is designed for a lawyer who understands how data centers are developed and operated—not a general real estate practitioner. You will work closely with infrastructure, finance, procurement, and operations teams, while coordinating outside counsel where appropriate, to help projects move quickly and responsibly. San Francisco is preferred, and occasional travel may be required. In this role, you will: Lead commercial legal strategy and risk management for data center development and colocation transactions. Draft, negotiate, and advise on colocation agreements, construction agreements, power-related arrangements, and other contracts supporting data center development. Support first-party projects involving raw land, site and power rights, design and construction, EPC models, third-party build-to-suit structures, and leasebacks. Partner cross-functionally with infrastructure, finance, procurement, operations, and other stakeholders on fast-moving, complex projects. Manage and collaborate effectively with outside counsel across a high volume of infrastructure matters. Develop scalable legal playbooks and contracting approaches for a growing portfolio of data center sites. You might thrive in this role if you have: 12+ years of legal experience, primarily in commercial legal roles. Deep, hands-on experience

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. Our Communications team includes External Communications, Internal Communications, and other strategic communications functions. This team’s ethos is to support OpenAI's mission and goals by clearly and authentically explaining our technology, values, and approach to safely building powerful AI. About the Role We’re looking for a senior communications leader to shape how OpenAI communicates about its emerging ads and monetization business. This person will define the global narrative, lead communications for major product and business milestones, and build sustained programs that explain our approach to ads and monetization clearly and credibly. The role will be central to showing how OpenAI can develop advertising experiences that are useful to people, valuable to businesses, transparent in how they work and consistent with our mission. You will work closely with Product, Go-to-Market, Marketing, Policy, Legal and Partnerships to anticipate opportunities and risks, develop integrated campaigns and help the business scale with trust. You will also serve as a trusted advisor to senior leaders on positioning, reputation, media strategy and the broader industry conversation. This is both a strategic and hands-on role. The right person will be comfortable defining a long-term communications strategy, building the systems and relationships needed to execute it, and personally leading through high-profile launches and fast-moving issues. This role reports to the VP of Communications and is based in San Francisco, CA. We use a hybrid work model of four days per week in the office and offer relocation assistance In this role, you will: Define and lead communications strategy for OpenAI’s ads and monetization initiatives, from global narrative development through launches and sustained storytelling. Build a clear, differentiated story about how OpenAI approache

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking a Senior Actuator Design and Integration Engineer to lead the development of custom electromechanical actuators for advanced robotic systems. You will own actuator development from early architecture and concept generation through prototype validation and system integration, partnering closely with mechanical, electrical, controls, firmware, reliability, and manufacturing teams. This role focuses on the design, integration, and validation of precision electromechanical systems, including motors, transmissions, sensing, structural components, and thermal architectures. You will help drive actuator development across the full engineering lifecycle while establishing scalable design, test, and integration practices for future robotic platforms. This role is based in San Francisco, CA, and requires in-person presence 4 days a week. In this role, you will Lead the architecture, design, and integration of custom robotic actuators, including motors, transmissions, sensing, thermal systems, structural components, and packaging. Define actuator requirements and system-level trade studies around torque density, bandwidth, efficiency, thermal performance, backdrivability, inertia, reliability, manufacturability, and cost. Design precision electromechanical assemblies with strong attention to tolerances, alignment, load paths, thermal expansion, sealing, wear, and serviceability. Drive actuator integration into robotic systems, partnering closely with controls, firmware, electrical, and robotics software teams to optimize closed-loop pe

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking a Senior Mechanical Engineer to lead the design, integration, and sustaining engineering of mechanical subsystems in robotic platforms. You will work closely with experienced engineers and cross-functional partners to set functional requirements, develop and iterate on hardware to meet program expectations. This role is aimed at candidates with strong fundamentals in mechanical system design — including tolerance, alignment, load paths, wear, and failure modes — and robotics. You will contribute to real hardware programs moving from prototype through early production. You will lead both new subsystem development and ongoing improvements to existing systems based on testing, field performance, and manufacturing feedback. This role is based in San Francisco, CA, and requires in-person presence 4 days a week. In this role, you will Lead the design and iteration of mechanical subsystems, including structures, mechanisms, and actuators. Create and maintain CAD models, assemblies, and drawings with appropriate tolerancing and documentation. Build and test prototypes, supporting debugging of mechanical issues such as fit, alignment, friction, and wear. Assist in developing test methods and executing validation to evaluate performance, durability, and failure modes. Work with cross-functional teams to integrate mechanical components with sensors, actuators, and control systems. Support transition of designs from prototype to manufacturable assemblies, incorporating DFM and DFA considerations. Collaborate with manufacturing partners

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team OpenAI’s Hardware organization develops system and infrastructure solutions designed for the unique demands of advanced AI workloads. We work closely with architecture, infrastructure, and vendor teams to evaluate system performance and guide critical design decisions. Our team focuses on building and applying performance modeling frameworks to understand system behavior, quantify tradeoffs, and support next-generation infrastructure design. About the Role We are seeking an Performance Modeling Engineer to support the development and application of modeling tools used to evaluate AI system performance and inform architectural decisions. In this role, you will partner closely with Senior Performance Modeling Engineers and the Performance Modeling Lead to analyze system behavior, run simulations and analytical models, and help evaluate tradeoffs across compute, memory, networking, and storage. You will contribute to building modeling frameworks while developing a strong foundation in system architecture and AI infrastructure. This role is ideal for early-career engineers with 1–2 years of experience in software engineering, systems analysis, or performance modeling who are excited to grow in large-scale infrastructure and hardware/software systems. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance. Key Responsibilities Support the development and maintenance of performance modeling tools and frameworks Assist in building models to evaluate system behavior across compute, memory, networking, and interconnect subsystems Help analyze distributed system scaling behavior and identify performance bottlenecks Run simulations and analytical models to support architecture and infrastructure decisions Partner with senior engineers to evaluate design tradeoffs across hardware and system components Interpret modeling outputs and help translate findings into clear recommendations Vali

AWSRestAIRust
A
📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: MAIN PURPOSE OF ROLE We are seeking a high caliber and ambitious Supply Chain Manager to join our team in Sylmar, CA . The Supply Chain Manager of Lifecycle Management will support the lifecycle of our product supply, including but not limited to New Product Introduction (NPI) and End of Life (EOL) product planning alignment. The lead in this role supports new product development (NPD), product transfer, and engineering projects and is responsible for managing and executing all supply chain requirements and objectives to support overall business objectives. This position provides an opportunity for key talent to develop toward future Supply Chain or Operations Leadership roles within the business. The role will have significant visibility to Senior Management and carries high expectations. This position will also have people leader responsibilities for highly skilled direct report(s). MAIN RESPONSIBILITIES Manages supply chain program/product lifecycle management processes and execution for NPD and EOL. Engages planning teams to develop demand and supply plans during the new product development and EOL processes. Engages commodity managers and buyers during the design phase (early supplier involvement) and serves as a key participant in supplier selection for the program. Coordinates material purchasing schedules and inspection releases, working closely with cross-functional supply chain and supply quality groups. Assesses EOL and last-tim

Supply ChainProcurementCustomer ServiceCRM
C-
📍 Miami, Florida, United States
✓ High-confidence listing

$250K – $300K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. The Vice President, Operations - South will lead CLEAR’s airport operations across our South region, with responsibility for delivering exceptional security, member experience, sales, and people outcomes. You’ll lead a large organization of frontline team members and general managers while driving growth, operational excellence, and a high-performing culture across the region. This is a key role on our Airport Operations leadership team. What you'll do: Own operational and financial performance across CLEAR’s South region, delivering against security, member experience, enrollment, sales, labor, and profitability goals Lead, coach, and develop Regional Directors and General Managers, building a strong leadership bench and driving clear accountability and consistent execution across the region Drive regional growth by maximizing performance at existing airports, supporting new airport launches, and accelerating adoption of new products and experiences Build trusted relationships with senior airport, aviation, and internal stakeholders, representing CLEAR at the executive level and aligning partners around shared business and operational priorities Partner cross-functionally with People, Training, Compliance, Member Experience, Finance, and other teams to strengthen execution, develop talent, uphold CLEAR’s standards, and continuously improve the member and team member experience How you'll measure success: Security and compliance performance across all airports within the South Achievement of regional balanced scorecard tar

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