Jobs in United States

Senior Lead Technical Program Manager Knowledge Systems in United States

1,941 active opportunities · Updated October 2026

Explore current senior lead technical program manager knowledge systems jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

43/100

watch · 145 related jobs

Hiring trend

-65.7%

Job postings compared with the previous 30 days

Remote options

20.7%

Share of matching jobs listed as remote

Typical salary

$145.7K – $145.7K/yr

Based on 9 salary observations

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📍 Kentucky, United States· Remote
✓ High-confidence listingCompany trend +671.4%

$108.6K – $250.7K/yr

Quick readStrong listing-quality and freshness signals

Pfizer US/PR Commercial Sales Founded in 1849, Pfizer Inc. began as a small chemistry enterprise built on the belief that scientific ingenuity can improve—and protect—human life. Today, as one of the world’s leading biopharmaceutical companies, Pfizer’s purpose is Breakthroughs that change patients’ lives : discovering, developing, and delivering medicines and vaccines that address unmet need, earn trust through quality and integrity, and reach patients through strong partnerships across the healthcare system. In a complex and rapidly evolving pharmaceutical landscape, our work is measured by one outcome - helping patients live longer, healthier lives . Rare Disease Sales Organization Mission & Impact Pfizer’s Rare Disease – Rare Cardiac Sales organization exists to help improve the lives of people living with serious rare cardiac conditions by connecting scientific innovation to the clinicians and systems that deliver care. We lead with integrity and patient need— advancing disease and product education grounded in robust clinical evidence , promoting Pfizer Rare Cardiac therapies compliantly, and supporting healthcare professionals’ understanding of appropriate patient identification and use based on approved indications. Through evidence‑based scientific exchange, we help reduce access, diagnostic, and workflow barriers so more patients can start and stay on the right therapy. Our impact is more informed clinical decision ‑ making, improved consistency of care, and better outcomes for patients , contributing to a higher standard of care across the rare cardiac community. Role Summary The Rare Disease – Rare Cardiac, Senior Health & Science Specialist is a field-based specialty sales role responsible for driving the growth of Rare Cardiac products through compliant, strategic relationships within assigned accounts. This role par

AIRecruitment
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -82%
Quick readStrong listing-quality and freshness signals

About the Role As Head of Finance - Data Centers, you will be the finance leader for OpenAI’s self-built data center efforts. You will partner with teams across infrastructure, real estate, energy, construction, procurement, and finance to turn proposed sites into sound investment decisions and funded projects. This role spans the full development lifecycle: evaluating opportunities, building investment cases, forecasting capital needs, managing construction budgets, and helping determine how projects should be financed. You will give leadership a clear view of project economics, funding requirements, and risks as we build data center capacity at scale. In this role, you will: Lead financial evaluation of proposed data center and related power infrastructure projects, including site economics, development costs, capacity phasing, lifecycle costs, and key risks. Build and own project-level models and capital expenditure forecasts that connect construction schedules, power delivery, equipment procurement, contingencies, and funding needs. Establish capital budgets and financial controls for active builds. Track commitments, actual spending, change orders, and forecasts to completion; identify cost or schedule risks early. Partner with development, engineering, energy, construction, and procurement leaders on decisions that affect cost, timing, and long-term performance. Work with Treasury, Corporate Finance, Tax, and Legal to evaluate financing options, including project or construction debt, leases, joint ventures, and other partnership structures where appropriate. Prepare investment recommendations and capital approval materials for senior leadership, translating complex project details into clear choices and tradeoffs. Build a consistent portfolio view of project costs, cash requirements, milestones, and financial performance. Partner with Accounting and operations teams through project completion and handoff. You might thrive in this role if you have: Prior exper

AWSRestAIRust
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📍 Austin, Texas, United States· Full-time
✓ High-confidence listing

$100K – $500K/yr

Quick readStrong listing-quality and freshness signals

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. We are seeking a Senior Cost Accounting Manager to join our world-class accounting team. You will play a critical role in owning manufacturing cost accounting — including inventory, fixed assets, and COGS — building out standard cost processes, and partnering cross-functionally with Supply Chain, Sales, and R&D to drive accurate, scalable financial reporting as we grow toward IPO readiness. This role is hybrid, based out of Austin, TX; Santa Clara, CA; or Toronto, ON. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are Accounting or Finance degree; CPA strongly preferred. 8+ years in manufacturing or hardware cost accounting. Deep U.S. GAAP knowledge for inventory, fixed assets, and COGS. Expert with standard costing, variance analysis, and cost roll-ups. Comfortable turning Supply Chain, Sales, and R&D activity into accurate results. What We Need Own inventory, fixed asset, and COGS accounting under U.S. GAAP. Build and scale the cost accounting function for IPO readiness. Maintain and improve standard costs, updates, and cost roll-ups. Analyze manufacturing variances and partner with Operations on actions. Lead COGS and mar

AWSAISEMAccounting
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📍 Foster City, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -85.9%
Quick readStrong listing-quality and freshness signals

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. About the role: We're hiring a Product Partnerships Manager to own Replit's most important strategic partnerships end-to-end: from identifying the opportunity to shipping the outcome and measuring the impact. This is a product-focused role where you will work with our consumer technology partners, such as Stripe, Shopify, Google, and the broader connector ecosystem. You'll work at the intersection of product strategy, ecosystem thinking, and deal execution. You'll need to be a serious Replit power user. You'll speak credibly with engineers. You'll negotiate with senior partner stakeholders. And you'll be the person accountable for turning ambiguous ecosystem opportunities into shipped product and business outcomes. What You'll Do Develop a clear point of view on Replit's partner landscape and build a prioritized pipeline of high-leverage opportunities across consumer tooling, AI tooling, cloud and infrastructure, and payments technology partners. Lead partner conversations from early exploration through joint product thesis, business case, commercial terms, launch plan, and post-launch iteration. Partner with Product, Engineering, Partner Engineering, Legal, Finance, Marketing, and Sales to turn agreements into shipped outcomes. Work directly with Partner Engineers to scope integrations, demos, prototypes, reference apps, and partner enablement assets. Define success metrics before every launch activation: retained usage, apps created, deployments, revenue, partner-sourced users, and use them to decide when to scale, iterate, or sunset a partnership. Build lightweight operating systems: partner scorecards, launch checklists, partner roadmap tracking, and repeatable frameworks for evaluating new opportunities. Represent

AIGoRustMarketing
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -82%
Quick readStrong listing-quality and freshness signals

About the Role OpenAI’s Applications organization spans rapidly growing Consumer, Enterprise, Developer, and Hardware businesses. As we scale across EMEA, APAC, and LATAM, we’re building the financial and operating model that will help our regional teams make faster, better decisions. We are hiring a senior Strategic Finance partner to help shape that work. You’ll serve as a trusted advisor to regional GMs, connecting market strategy with business performance and guiding where and how we invest. By bringing together insights across growth, revenue, OpEx, headcount, and marketing effectiveness, you’ll help leaders understand market health, set priorities, and drive measurable outcomes. You’ll create the frameworks, operating rhythms, and decision processes needed to scale our international business, while contributing to broader Strategic Finance priorities across Marketing. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Periodic international travel is expected. In this role, you will: Own an integrated view of OpenAI’s international performance—spanning countries, regions, and Consumer, Enterprise/API, and Developer businesses—to guide growth, resource allocation, and investment decisions. Partner with regional GMs and functional leaders to shape country strategies spanning Product, Sales, Growth and Brand Marketing, Partnerships, Communications, and Policy. Lead regional financial planning and forecasting, tracking budgets, headcount, capacity, investments, and risks against the company plan. Build and operationalize investment frameworks across markets, channels, and programs, evaluating expected returns, opportunity costs, and tradeoffs to recommend what to fund and when. Create regional and country scorecards and lead regular business reviews that track key metrics, surface risks, drive decisions, and ensure follow-through. Design decision rights and escal

SQLAWSRestAI
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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -82%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s mission is to ensure the responsible and widespread adoption of artificial intelligence. In support of that mission, the Marketing team helps deeply understand customer audiences and market dynamics, influence the development of the right products, build sustainable and customer-aligned monetization models, and drive awareness, adoption, and usage across OpenAI’s products and platform. We take a data-driven approach to understand markets, develop monetization strategies, and uncover customer needs that shape product strategy and messaging. We partner closely with Sales, Partnerships, Product, Engineering, Research, Comms, and Design to deliver a cohesive end-to-end customer experience and lead go-to-market efforts for new product launches across channels. About the Role We’re looking for a Marketing Scientist to join OpenAI’s Ads Marketing Science function. Reporting to Marketing Science leadership, you’ll be a senior individual contributor who combines rigorous measurement expertise with strong client judgment and hands-on execution. Your mission is to help OpenAI Ads prove and improve advertisers’ media performance. You’ll work with sales, partners, and clients supporting all forms of measurement including verification, attribution, incrementality, brand, marketing mix modeling (MMM), and scalable advertiser reporting, connecting sound methodology to decisions advertisers can act on. You will partner closely with Sales on key advertising accounts and with Product, Engineering, Data Science, Partnerships, Legal, and Privacy. Initial priorities include advancing incrementality measurement, helping onboard measurement partners to privacy-forward measurement workflows and integrations, and creating reusable programs, tools, agents, skills, and workflows that let sales and clients access high-quality Marketing Science support at scale. This role is based in either San Francisco or New York, and follows a hybrid schedule (Monday-Wednesday). In th

PythonSQLAWSRest
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📍 San Francisco, CA, United States· Full-time
✓ High-confidence listingCompany trend -91.7%
Quick readStrong listing-quality and freshness signals

For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. Smartsheet is seeking an experienced sales leader to lead a team of Account Executives as a Regional Director, Enterprise-West. The ideal candidate will have a history of building and leading teams to overperform in quota attainment, close transformational transactions, and align strategically with large customers. This role is part of the Enterprise Sales organization and is West Coast based in your own remote home office. You Will: Build and lead a Sales team to exceed quarterly and annual sales quotas Effectively predict and deliver sales results through accurate monthly, quarterly, and annual sales forecasting Serve as player/coach in the execution of a complex, solution­-based sales process encompassing multiple groups within Large Enterprise accounts Play a leadership role in developing new business opportunities by coaching Account Executives to build and execute account-focused strategies Drive Smartsheet senior executive engagement in target accounts Successfully execute across all disciplines of sales management, including Account/Opportunity/Relationship planning and sales methodology execution Partner with Sales Engineering, Consulting, Customer Success and Marketing management to identify and close software and professional services solutions in Large Enterprise accounts Proactively identify and address issues that will increase growth velocity in the assigned sales region Other duties as assigned Travel as needed (30-50%) You Have: 10+ years of experience in the software industry with curr

AWSAIExcelMarketing
M
📍 Boise, ID - ID1, United States
✓ Quality checkedCompany trend -75%

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. The Site Inventory Control (SIC) team is at the forefront of our ambitious expansion efforts. SIC plays a pivotal role in connecting wafer starts, inventory strategy, cycle time management, output delivery, and factory execution. As a Senior Engineer for Fab 4 HVM SIC, you will be the operational hub, driving alignment between Technology Development (TD), High Volume Manufacturing (HVM), Probe, Supply Chain, Planning, and Engineering organizations. This outstanding opportunity allows you to lead the charge in optimizing inventory and cycle time performance while ensuring flawless factory execution! We are looking for individuals who thrive on collaboration and tackling complex operational challenges. You'll have the chance to bring to bear data to drive decisions and implement AI-enabled solutions to improve speed, accuracy, and decision-making. Responsibilities: Lead multi-functional initiatives for wafer starts, inventory, cycle time, and output performance to support business commitments Develop and improve inventory control methodologies, business processes, and operational metrics and recommend corrective actions Develop and implement inventory, priority, and capacity strategies for New Product Introduction (NPI) programs Foster coordination between Technology Development, High Volume Manufacturing, Supply Chain, Planning, and Engineering teams to optimize inventory positions and factory flow Identify and mitigate constraints, risks, and op

PythonSQLAIPower Bi
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📍 San Francisco, CA, United States
✓ Quality checkedCompany trend -95.5%

Employee Applicant Privacy Notice Who we are: Shape a brighter financial future with us. Together with our members, we’re changing the way people think about and interact with personal finance. We’re a next-generation financial services company and national bank using innovative, mobile-first technology to help our millions of members reach their goals. The industry is going through an unprecedented transformation, and we’re at the forefront. We’re proud to come to work every day knowing that what we do has a direct impact on people’s lives, with our core values guiding us every step of the way. Join us to invest in yourself, your career, and the financial world. The Role: Positioned in the first line of defense (1LOD) and reporting to the Head of Business Controls, this experienced executive will act as the Business Controls Lead for SoFi’s Technology and Cybersecurity organizations. This includes comprehensive coverage of Engineering, Information Security, Infrastructure, and Data across the full SoFi Legal structure: SoFi Inc., SoFi Bank, Galileo, Technisys, and SoFi Hong Kong. The Business Controls Lead will act as the direct advisor to the Chief Technology Officer (CTO), Chief Information Security Officer (CISO), and their senior leadership teams. You will lead a team of experienced IT risk & controls team charged with promoting risk awareness and ensure the overall effectiveness of risk and compliance management program implementation and execution across the 1LOD. This role provides support, advisory services, and enables strategic alignment directly to department heads to accelerate and ensure quality execution. You will be responsible for supporting and driving consistent 1LOD adherence to critical programs, such as building and maintaining risk and control self-assessments (RCSAs); identification and evaluation of control effectiveness through control testing; 1LOD risk reporting; and supporting audits and regulatory exams. You will monitor the first l

AIFinanceSupply Chain
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📍 Boston, MA, United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 What You’ll Own Lead, coach, and develop a team of Account Executives focused on the commercial segment across AMER. Drive pipeline generation, deal execution, and consistent attainment of regional revenue targets. Build a strong operating cadence around forecasting, pipeline inspection, deal reviews, rep development, and performance management. Hire, ramp, and retain high-performing talent while creating an ambitious, inclusive, and motivating team culture. Improve sales process scalability through better use of CRM data, performance metrics, and repeatable best practices. Partner closely with Growth, Marketing, Operations, and Product to improve conversion, support important accounts, and remove friction in the customer journey. Reinforce high standards for thoughtful, value-based selling and customer-first leadership. Report on performance, pipeline health, forecast accuracy, and improvement opportunities to senior leadership. Required Qualifications Significant experience leading B2B SaaS sales teams in a commercial, SMB, or mid-market motion. Strong understanding of selling across AMER markets and how regional nuance shapes coaching, hiring, and execution. Proven track record coaching high-performing sellers and improving team productivity, forecast quality, and revenue outcomes. Experience building or scaling repeatable new-business and outbound motions. Strong analytical and operational instincts, with comfort using CRM data, sales metrics, and pipeline insights to drive decisions. Excellent communication, collaboration, and change-management skills. Ability to influence partners across Marketin

AWSMachine LearningAIGo
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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.6%

$220K – $300K/yr

Quick readStrong listing-quality and freshness signals

About Sentry Software runs the world and the pace is faster than ever. Sentry helps developers fix errors and performance issues before users notice, so teams can spend less time firefighting and more time building. Trusted by 200,000+ organizations, Sentry is today’s application monitoring standard and our team is building its AI-native future. About the role Developer experience at Sentry spans four areas: the integration and developer platform, docs, community, and DevRel. The DevEx team is responsible for how developers first encounter Sentry, how they learn to use it, and how they build on top of it — from SDK configuration docs to the Discord community to the integrations ecosystem. This role owns all of it. We recently had our Head of DevEx depart, and we're looking for a senior leader to step in with real ownership and real scope. You'll sit in Marketing, partner closely with EPD, and have direct influence over both the product surface (the integration platform) and the team responsible for developer education, docs, and community. In this role you will Own strategy and execution for Sentry's integration ecosystem and developer platform APIs — working closely with EPD to define the developer-facing surface and ensure building on Sentry is a genuinely good experience Lead the documentation function across SDK configuration docs, API reference, and tutorials — the places where developer activation actually happens or doesn't Connect docs to the product experience: logged-in state, contextual guidance, health checks, and surfacing adoption gaps in-context, in partnership with EPD and the Docs platform team Own Sentry's developer community across Discord, social, and events, and build the team and processes that turn engagement into measurable outcomes: signups, adoption, support deflection Build and deliver the content and education programs — workshops, deep dives, fireside chats — that teach developers tracing, debugging, and how to actually use Sentry's full

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -72.3%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. We turn Plaid's product expertise, proprietary data, customer impact, and perspective on intelligent finance into stories that build understanding, trust, and demand. We sit within Brand Marketing, owning resource content, customer storytelling, and owned editorial franchises, and we're increasingly bringing that storytelling to life through video and audio. You'll join as our first dedicated video and audio producer, reporting to our incoming Content Lead. You'll jump in immediately to produce Intelligent Finance, our flagship podcast and video series hosted by CEO and co-founder Zach Perret, already in production, so you'll pick up the reins without a long ramp-up period. You'll own production end-to-end, partner closely with our Content Design team to shape stories, and work directly with senior leaders to translate our product, data, and industry perspective into content people actually want to watch and listen to. Responsibilities: Immediately step in to produce Intelligent Finance, our already-underway podcast and video series, with no ramp-up period. Own end-to-end production of Plaid's flagship video and audio content, from concept through final delivery. Partner closely with Content Design

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📍 United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Own and evolve the Quality Management System (QMS) to support a regulated medical device development program, including design controls and DHF maintenance. Establish and enforce requirements traceability: user needs → design requirements → verification/validation artifacts and change control. Define and run the program-level V&V strategy (verification, validation, and test coverage), including test plans, protocols, reports, and acceptance criteria. Drive risk management activities (e.g., DFMEA / PFMEA, hazard analyses) and ensure mitigations are reflected in requirements and verification. Lead document control: reviews, approvals, training, retention, and audit readiness. Partner with engineering to make quality “native” to the dev workflow (automated testing, release gates, software configuration management). Prepare the program for audits and inspections, including hands-on audit leadership. What we’re looking for Senior experience leading quality for complex hardware + software products in a regulated environment. Deep familiarity with design controls, DHF, document control, risk management, and verification planning. Strong systems thinking and the ability to translate ambiguous product intent into testable requirements. Comfortable collaborating directly with multidisciplinary engineering (recon/ML, embedded, mechanical, EE, cloud). Useful experience Regulated product quality leadership (ISO 13485 / 21 CFR 820 or equivalent), including audit readiness and FDA-facing work. eQMS + document control fluency (e.g., Greenlight Guru) that integrates cleanly with modern engineering workflows.

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📍 California, United States· Full-time
✓ Quality checkedCompany trend -72.3%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. Plaid is in one of the most exciting chapters in its history — and this role exists to make sure every Plaid employee feels it. As Internal Communications Lead, you'll build and own the systems, channels, and programs that keep Plaids informed, aligned, and energized about our mission and the opportunity ahead. This spans employee-facing comms and programming across channels, including programming and producing monthly All Hands and Half-yearly Business Reviews, and supporting leaders with change management. This is a builder role: you'll take what exists and programmatize it, defining the infrastructure, cadences, and editorial strategy that elevate how we communicate as a company. You'll play a central role in shaping Plaid's internal AI narrative, helping employees understand where AI is taking us and what it means for their work. You'll operate as a trusted advisor to Plaid's executive team and founder CEO, with the exec presence and judgment to counsel leaders on high-stakes moments. You will also work closely with senior leaders across the org as well as cross functional partners across the people team (Chief People Officer, HRBPs, WPE, Comp, Learning and Development) Responsibilities : Execut

AWSAIGoRust
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📍 United States· Full-time
✓ Quality checkedCompany trend -95.5%

Employee Applicant Privacy Notice Who we are: Shape a brighter financial future with us. Together with our members, we’re changing the way people think about and interact with personal finance. We’re a next-generation financial services company and national bank using innovative, mobile-first technology to help our millions of members reach their goals. The industry is going through an unprecedented transformation, and we’re at the forefront. We’re proud to come to work every day knowing that what we do has a direct impact on people’s lives, with our core values guiding us every step of the way. Join us to invest in yourself, your career, and the financial world. The Role Senior Payroll Tax Specialist SoFi is searching for a Senior Payroll Tax Specialist to manage and optimize our payroll tax operations. This role is a key member of the Payroll Team, responsible for validating tax calculations, ensuring filing compliance and serving as the subject matter expert on payroll tax regulations and best practices. The Specialist will exercise independent judgment in interpreting complex federal, state, and local tax laws, advising Finance and HR on tax implications and driving process improvements to ensure absolute accuracy in our tax liabilities and reporting. Responsibilities Validate all payroll tax calculations, filings, and payments to ensure full compliance with statutory regulations. Research and interpret complex payroll tax laws and updates, advising stakeholders on the implications of policy or program changes. Prepare comprehensive reports for Finance and leadership regarding tax liabilities, labor costs, and tax-related trends. Support and lead internal and external payroll tax audits, including detailed documentation and issue remediation. Develop and maintain robust payroll tax controls to support audit cycles and SOX compliance. Oversee the end-to-end US bi-weekly payroll processing as a backup to the Payroll Specialist as needed. Maintain expert knowledge

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