Jobs in United States

Senior System Software Safety Engineer in United States

2,189 active opportunities · Updated October 2026

Explore current senior system software safety engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team Like every team at OpenAI, the Marketing team contributes to our broader mission of ensuring responsible and widespread adoption of artificial intelligence. With that aim in mind, we are responsible for developing and executing strategies that drive awareness, engagement, and usage for OpenAI’s products and platform amongst our core audiences. Our focus extends beyond just promoting product features; we aim to provide valuable insights and resources that help our users make the most out of AI technologies. About the Role As an Industry PMM, you will help define how OpenAI brings frontier AI to priority industries. This role sits at the center of OpenAI’s industry marketing motion, helping customers understand where AI can create practical value, improve workflows, and support responsible adoption. You will shape the market narrative, build the field-facing operating system, and coordinate cross-functional execution across product launches, customer proof, partner moments, events, and account-based campaigns. You will help senior industry leaders understand how OpenAI models, products, and workflows can support meaningful work in either Life Sciences, Banking, or Healthcare. We’re looking for a product marketer who can combine strategic narrative, technical curiosity, enterprise GTM judgment, and program leadership. The right person can turn fast-moving capability into clear positioning, credible assets, and practical field execution. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Own positioning and messaging for OpenAI’s industry offering for either Life Sciences, Banking, or Healthcare. Build field-ready assets for account directors, solution engineers, industry leaders, and executive audiences, including first-call decks, one-pagers, use-case libraries, customer stories, and proof-point packages Translate frontier model ca

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. Key focus areas include: catastrophic risk, mental health, teen safety and multimodal safety. About the Role Providing access to frontier AI systems raises complex questions around dual-use science and catastrophic risk. How should models respond to requests involving chemical synthesis, biological experimentation, or pathogen research? Where is the boundary between legitimate scientific inquiry and information that could enable misuse? How do we design policies that meaningfully reduce risk without unnecessarily restricting beneficial research? This is a senior role in which you’ll help shape policy creation and development at OpenAI for addressing biological and chemical risks. You will develop structured policy frameworks and taxonomies to guide safe model behavior. This role sits at the intersection of biosecurity expertise, AI safety research, and policy design. You will help ensure that frontier AI systems can support beneficial life sciences research, such as drug discovery, public health, and biosafety, while reducing the risk that these capabilities could be misused. Our relevant publications: Preparedness framework Preparing for future AI capabilities in biology Safety evaluations hub OpenAI GPT5 System Card Evaluating Fairness in ChatGPT Improving Model Safety Behavior with Rule-Based Rewards OpenAI Model Spec Your Responsibilities: Design and maintain model policies governing chemical and biological risk, defining how models should safely handle dual-use scenarios. Develop structured taxonomi

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -88.6%

From $245K/yr

Quick readStrong listing-quality and freshness signals

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role Notion is looking for a Head of Demand Engine to build the engine that turns our best product stories, customer proof, and market opportunities into scaled pipeline. You’ll lead demand programs across campaigns, digital, paid strategy, webinars, email, web, and emerging channels. You’ll partner closely with Product Marketing on audience and offer strategy, with Performance Marketing on paid execution, and with Field Marketing & Events on the moments that benefit from in-person activation. This is a senior leadership role with both AMER and global scope. You’ll help set the global standard for how Notion plans, runs, tests, and measures demand programs, while learning from strong regional teams and making the best ideas repeatable across markets. You’ll lead a growing team spanning demand programs and digital demand, with room to expand into areas like partner marketing over time. This is a build job as much as a run job. We’re looking for someone with real taste who can spot a strong idea, turn it into a sharp program, and build a repeatable engine around what works. You should care about quality and craft, but als

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -88.6%

$140K – $195K/yr

Quick readStrong listing-quality and freshness signals

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role: Notion is looking for a Recruiting Program Manager to help design, build, and scale the systems and programs that power how we hire. This is a role for someone who moves fast, takes ownership, and doesn't wait to be told what to do — someone who operates with both strategic altitude and operational precision, and knows how to bring clarity and momentum to complex cross-functional work. We're at an inflection point in how we think about recruiting at Notion, and this role sits at the center of it. You'll partner closely with Recruiters, Recruiting Operations, People Operations, and senior leadership to drive some of our highest-priority initiatives — building the programs and processes that define how Notion finds, evaluates, and brings in exceptional talent. This role can be based in either San Francisco or New York City. We work from our offices on Mondays, Tuesdays and Thursdays (our Anchor Days) because we do our best thinking and building together in person. We’re looking for someone who’s excited to work alongside the team during those days. What You'll Achieve: The scope of this role will evolve with the team's

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📍 New York, New York, United States
✓ Quality checkedCompany trend +212.5%

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Manager, Corporate Treasury Overview Mastercard is looking for a Manager, FX Trading & Strategy to join the New York City office and oversee daily FX trading, risk management and support the implementation of new processes and procedures. The responsibilities for this role include: • Develop new foreign exchange capabilities to support business initiatives involving cross-border payments • Define FX desk workflows, policies, procedures, and implement a high level of automation • Execute the company’s foreign exchange risk management program and strategies • Monitor FX trade executions and open positions • Measure FX risk according to company policy and report exposures to senior management • Analyze approaches to optimize risk management • Onboard trading partners • Identify requirements to trade exotic currencies • Support the testing of FX risk management, quoting, and trading systems • Communicate relevant news, market events, and FX system behavior to team members • Analyze market trends (liquidity, spreads, volatility, etc.) for the business • Evaluate business cases for incremental revenue opportunities related to foreign exchange transactions and support the business with project-based FX analysis • Contribute to all aspects of the trading desk activities incl

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📍 California, El Segundo, United States
✓ High-confidence listingCompany trend +5.2%

$115.3K – $149.2K/yr

Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Position Summary The Senior IT Quality Engineering Specialist serves as the technical lead for the Kite Laboratory Information Management System (KLIMS) within North America West Coast (El Segundo). This role is responsible for the operational stability, compliance, maintenance, enhancement, and technical governance of the LabVantage platform and associated integrations. The position partners closely with Quality Control, Manufacturing, Validation, Infrastructure, and Kite Business stakeholders to ensure reliable and compliant laboratory operations. Key Responsibilities System Administration & Operational Support • Provide day-to-day administration and technical support for KLIMS and related

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📍 Bothell, Washington, United States
✓ High-confidence listingCompany trend +3.1%

$105K – $168K/yr

Quick readStrong listing-quality and freshness signals

Job Title Project Manager Job Description 589963 Project Manager – Bothell, WA As a Project Manager, you will lead and execute multi-discipline projects, ensuring successful delivery across scope, schedule, budget, quality, resources, and risk while aligning project outcomes with Philips business objectives. Your role: Initiate, plan, and execute multi-discipline projects in accordance with agreed specifications, timelines, budgets, staffing requirements, and quality standards, ensuring successful delivery and stakeholder satisfaction. Manage and balance project scope, schedule, budget, quality, resources, risks, and issues throughout the project lifecycle while monitoring and optimizing the business case to maximize organizational value and impact. Build and maintain strong partnerships with internal and external stakeholders, manage expectations and customer feedback, proactively address issues, and provide detailed project progress, risk, and escalation reporting to senior management and steering committees. Apply and reinforce Philips project management standards and methodologies, including the Philips Business System (PBS), Philips Excellence Process Framework (PEPF), PMBOK, and SAFe, ensuring projects are executed in accordance with organizational expectations and industry best practices. You're the right fit if: You’ve acquired 2+ years of experience in project management, business strategy, or a related area with a Bachelor’s degree; no prior professional experience is required with a relevant Master’s degree. Your experience includes supporting or managing projects involving scope, schedule, budget, resources, risk, and multiple stakeholders. Your skills include project planning and execution, stakeholder management, risk and issue management, budget and resource management, c

Project Management
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📍 California, San Diego, United States
✓ High-confidence listingCompany trend -50%

$141.6K – $212.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Summary The Staff Data Engineer is a seasoned, hands-on engineer who designs, builds, and scales data products on our cloud lakehouse, powering analytics, reporting, and AI/ML across Illumina. We are looking for someone with strong proficiency in Python, SQL, and data modeling, a solid understanding of distributed systems and system design who has built and scaled data products on modern cloud platforms such as Databricks and Snowflake. This is a hands-on, senior individual-contributor role with end-to-end ownership and leadership spanning multiple domains such as Supply Chain, Manufacturing and Quality, including mentoring engineers on our global (India-based) team. Responsibilities Partner across business, AI, and platform teams translating domain needs (e.g., SAP, Manufacturing, Quality) into well-modeled, governed and scalable data products. Design, build, and scale end-to-end data products on Databricks (and interoperating with Snowflake) — from ingestion through curated, analytics-ready datasets following a medallion (Bronze/Silver/Gold) architecture. Develop reusable frameworks, libraries, and

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📍 Phoenix, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Title: Outreach Executive I Company: Oak Street Health Role Description: The Outreach Executive (OE) is responsible for developing relationships with members of the community to engage Medicare seniors with Oak Street Health. Outreach Executives should be engaging Medicare seniors with the goal of having those individuals become patients of Oak Street Health. Outreach Executives will work very closely with their Outreach Managers, Outreach Directors, and Community Relationship Managers to help drive new patient growth locally in their assigned territory. Core Responsibilities: Sales Generating leads by effectively engaging Medicare senior community through event execution and local community outreach Maintaining internal sales system knowledge and marketing programs by attending scheduled meetings to learn about new updates on services, workstreams, and initiatives Prospecting and cold calling to prospects & new leads assigned to you. Additional new channels of leads that are assigned to you may come from: Leads driven through Digital channels Leads generated by other Outreach Executives Nurturing prospective patients and prospect for new patients with an ambitious mentality via email, phone, and networking Collaborating with your Community Relation

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📍 Remote, United States· Remote
✓ Quality checkedCompany trend -13.7%

NVIDIA DGX Cloud is an AI Factory designed to power the next generation of AI and industrial-scale breakthroughs. As a Principal Engineer for Security Architecture, within our Security Engineering organization, you will own a core security domain of the AI factory: the architecture, the paved road that delivers it, and much of the code underneath. You will hold the security design bar across DGX Cloud from inside the teams doing the building, and this is a founding seat on a new team. Security Engineering is a new organization at DGX Cloud, accountable for the security outcome of the platform, and Security Architecture is the function inside it that holds the design bar. Security here is fleet horizontal and stack vertical, so your work will cross every DGX Cloud engineering organization: you will embed with the teams building GPU clusters, control planes, and services, join their designs as a participant rather than an approver, and leave behind systems in which an entire class of risk is no longer possible. There is no architecture review board here and no approval queue. You are a senior IC with deep security domain knowledge, and the security bar holds because you helped set it and then helped ship it. What You Will Be Doing: Own a Security Domain End to End: Take architectural ownership of a core domain of DGX Cloud security, from the design through the system running in production. That could be tenant and GPU workload isolation, workload identity, infrastructure and network, supply-chain provenance, hardened baselines and patching, or deploy-time policy and admission control. Embed with the Teams Building It: Join the design early, write the code, and help land it. The posture is not "you did this wrong." It is "here are the considerations we need to meet, I will help, let's go to work." Build Paved Roads, Not

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📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -93.3%
Quick readStrong listing-quality and freshness signals

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Our SI partners play a key role in bringing our customers' data-backed ambitions to life by implementing and harnessing the power of the Snowflake AI Data Cloud for cutting edge workloads and use cases. Through our partnerships, we enable companies to empower their employees with the data they need when and how they need it to better engage their customers, optimize their operations, and transform their products. The Partner Development Senior Manager role involves driving and nurturing relationships with our System Integrator (SI) partners. Your primary objective is to strengthen and expand the collaboration between Snowflake and these partners to drive growth. In this role you will be responsible for growing the relationship with IBM in the Americas. The success of these partnerships is demonstrated by driving growth with our joint customers, delivering key Go-To-Market (GTM) programs, establishing critical executive relationships, enabling partners to grow their Snowflake competency, and delivering customer success. Your success depends on your ability to drive compelling business strategies, GTM motions and relationships with IBM. Strong communication, experienced strategic alliance leadership, and problem-solving skills are vital to excel in this role. HERE ARE SOME KE

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📍 New York, new york, United States· Full-time
✓ Quality checkedCompany trend -67.9%

About Us: AI needs a new infrastructure layer. We're building it at Modal. Every era of computing brought new workloads that previous infrastructure couldn't support: mainframes, databases, and the cloud. Each time, the company that rebuilt the layer underneath defined the decade. AI is no different, except it touches everything instead of one slice, and the window to build the layer underneath it is open right now. Our customers include category-defining companies like Lovable , Ramp , Cognition, DoorDash, and Suno. They rely on Modal for instant GPU access, sub-second container starts, and native storage, so it's simple to serve low-latency inference, fine-tune models, and access production-ready sandboxes at scale. We recently raised a $355M Series C at a $4.65B valuation, led by General Catalyst and Redpoint Ventures. We've crossed $300M+ ARR and grown fivefold since September. Our team includes creators of popular open-source projects (e.g., Seaborn , Luig i ), academic researchers, international olympiad medalists, and experienced engineering and product leaders with decades of experience. About Modal Design Modal is building the future of serverless computing, and the brand that carries that story is still taking shape — You'll join Modal's newly formed Brand team inside our design org as one of its first senior hires, working directly with the Director of Brand Design and Head of Design to build a brand developers recognize instantly and remember. The Role As a staff-level Brand Designer, you will have major influence over every brand surface: the marketing website, campaigns, events, editorial projects like the GPU Glossary and forthcoming publications, and out-of-home work as we scale into larger formats. You'll also be a beacon to external agencies, representing Modal's internal creative voice and making sure the work translates into a system we can actually build on. And as the studio grows, you'll help set its craft standard — guiding and mentoring earl

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📍 New York, New York, United States· Full-time· Remote
✓ Quality checkedCompany trend -73.5%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. At Plaid, our mission is to empower innovators by delivering access to the financial system. Since 2012 we've helped tens of millions of consumers live a better financial life and thousands of customers build a new financial future. We work with companies like PayPal, Rocket, H&R Block, and many of the largest banks in the US to make it easy for consumers to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Raleigh, Washington D.C., London and Amsterdam. The Account Management team in Plaid’s Enterprise Segment leverages deep product and industry expertise to help our customers build and scale technology solutions. We act as partners, advisors, and advocates for our customers to help shape how consumers interact with their finances. As an Enterprise Account Management Lead, you’ll be responsible for managing the team of senior account managers who are growing the revenue from the Enterprise customer base, as well as setting the vision and strategy to build long-term

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83%

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to to ship AI products. THE ROLE The Field Productivity & Enablement Lead is responsible for making our sales motion clear, practical, and repeatable. This person will help define how we sell at Baseten: how managers run the business, how reps qualify and advance deals, how sales works with FDE, product, marketing, and support, and how those expectations get turned into training and day-to-day habits. This is a senior individual contributor role for someone who excels at both strategy and execution. You'll shape the system, but you won't stop at slides or frameworks. You'll build the playbooks, run the training, coach to the behaviors, and help managers ensure the process is followed consistently. We're not looking for someone who wants to force-fit a single methodology onto the business. We're looking for someone who is fluent in MEDDIC/MEDDPICC, Command of the Message, Challenger, and similar approaches, and can take the best ideas from each, adapt them to a technical sales motion, and build an approach that fits how Baseten actually sells. You'll report to the Head of Enablement and Productivity. Frontline managers and reps are your primary customers. RESPONSIBILITIES Manage operating model. Define the core rhythms for frontline managers, including 1:1s, forecast calls, pipeline reviews, deal reviews, and coaching cadences. Create clear expectations for how managers inspect deals, coach reps, and drive consistency across the team. Sale

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -87.7%

From $174K/yr

Quick readStrong listing-quality and freshness signals

About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. At Flexport, we are building the unified Supply Chain Operating System for global trade. While traditional consulting firms deliver slide decks and walk away, Flexport’s Forward Deployed Consultants (FDCs) embed directly on the operational frontline alongside enterprise clients to architect, build, and deploy real-time supply chain solutions. Operating alongside a Forward Deployed Engineer (FDE), you are a senior technical subject matter expert sitting at the intersection of Operations Research, data science, supply chain strategy, and executive client delivery. You will embed with Fortune 500 retailers, high-tech manufacturers, and global brand leadership to audit complex logistics networks, identify multi-million-dollar cost leaks, and build executable optimization models that transform client supply chains. You will serve as the solution design lead across a set of Flexport capabilities: Order, booking, and shipment management Transportation planning, consolidation, and exception management Data integrations, workflow automation, and operational analytics You won't just analyze data in a vacuum: you will write Python scripts, design supply chain algorithms, whit

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