Strategic Deals And Commercial Architecture Lead in San Francisco

We’re looking for a strategic operator to help advance OpenAI’s life sciences capabilities and translate them into meaningful scientific and commercial impact. Working closely with research teams and external partners, you’ll identify opportunities to improve AI models, products, and supporting infrastructure, and lead partnerships and strategic initiatives that bring these capabilities into real scientific workflows. This role combines partnership development, strategic judgment, and hands-on execution. You’ll help determine where OpenAI can make the greatest contribution, identify the expertise and resources needed, and bring together the right partners to move from an idea to demonstrated impact. In this role, you will: Shape capability priorities. Work with research and cross-functional teams to identify and prioritize new life sciences capabilities, balancing scientific value, technical feasibility, and commercial potential. Build and execute partnerships. Develop data, research, and commercial partnerships with biotechnology companies, pharmaceutical organizations, and other participants in the life sciences ecosystem. Translate capabilities into real-world applications. Partner with external organizations to apply OpenAI’s technology in scientific workflows, evaluate its usefulness, and use those learnings to inform further development. Structure effective collaborations. Work with legal, finance, research, and other teams to define partnership scope, align incentives, and navigate data access, intellectual property, commercial terms, and governance. Lead strategic initiatives. Identify and own projects that advance scientific capabilities and create long-term value for OpenAI, including licensing, joint development, and new applications of AI. Drive operational execution. Establish clear objectives, milestones, and ownership; coordinate resources; and resolve obstacles across internal teams and external partners. Expand access to expertise. Identify gaps in

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem to accelerate customer success, enable responsible enterprise AI adoption, and drive durable growth in support of OpenAI’s mission. We work cross-functionally across Sales, Solutions, Product, Engineering, Security, Legal, Finance, Marketing, Operations, and Customer Success to translate strategic partnerships into measurable outcomes for customers. Global consulting and advisory partners are essential to helping enterprises move from AI strategy to production deployment. PwC brings global reach, deep industry and functional expertise, technology and transformation capabilities, and longstanding relationships with complex and regulated enterprises. This role will lead OpenAI’s global partnership with PwC and create the strategy, operating model, and field motions needed to turn that relationship into repeatable customer and commercial impact. This role is based in San Francisco, New York City, or Seattle. We use a hybrid work model of three days in the office per week. About the Role We are hiring a Partner Director, PwC to serve as the single accountable owner of OpenAI’s strategic relationship with PwC globally. You will define the partnership thesis and joint business plan, build executive alignment, activate PwC’s industry, advisory, technology, sales, and delivery organizations, and develop repeatable go-to-market motions that accelerate enterprise AI adoption. This is a strategic and hands-on leadership role. You will move fluidly between senior executive engagement, joint account and opportunity strategy, solution and delivery alignment, field enablement, governance, and day-to-day execution. Success requires a strong understanding of how a large, matrixed professional-services organization operates, commercial discipline, technical fluency, and the ability to align teams without relying on formal authority. The ideal candidate has led a high-impact global alliance with

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem that accelerates customer success, enables enterprise AI adoption, and drives durable growth in support of OpenAI’s mission. Cloud partners are central to how customers discover, purchase, deploy, and scale OpenAI solutions. We work across cloud providers and their field, product, marketplace, technical, and partner organizations to reduce friction for customers and create repeatable paths from initial interest to production impact. The team collaborates closely with Sales, Technical Success, Product, Engineering, Finance, Legal, Security, Marketing, Operations, and Customer Success to turn strategic cloud relationships into measurable customer and commercial outcomes. About the Role We are hiring a Partner Director, GTM Cloud Partnerships to shape and execute OpenAI’s go-to-market strategy with strategic cloud partners. You will own senior relationships across a portfolio of cloud providers and develop joint business plans that expand customer access to OpenAI’s products, generate partner-sourced opportunities, and accelerate enterprise adoption. You will translate company-level partnerships into practical field motions spanning account planning, co-selling, cloud marketplaces, customer procurement, technical enablement, solution development, and executive engagement. This is a highly strategic and hands-on role. Success requires executive presence, strong commercial judgment, cloud ecosystem expertise, and the operating discipline to coordinate complex initiatives across multiple partners, regions, and internal teams. The ideal candidate can move fluidly between long-term strategy and the detailed execution required to deliver measurable results. This role is based in San Francisco. We use a hybrid work model of three days in the office per week. In this role, you will: Own the strategic and commercial relationships with a top global cloud partner, establishing strong alignm

About the Team The Ecosystem AI Deployment Engineering (ADE) team supports strategic partners as they build high-quality technical integrations into ChatGPT and Codex. Our goal is to create products users depend on, drive adoption and retention, and build an ecosystem where partners win when OpenAI wins. About the Role We are looking for an AI Deployment Engineer to help strategic partners design, build, evaluate, submit, launch, and maintain high-utility plugins for ChatGPT and Codex. This is a hands-on, partner-facing product engineering role for someone who can contribute to the platform itself, lead sophisticated partner engagements, and translate ambiguous product needs into production-ready integrations. You will work across partner product and engineering teams and OpenAI's product, engineering, partnerships, legal, policy, design, and go-to-market teams. You will identify the right use cases, prototype and review implementations, run evaluations, debug issues across systems, guide partners through submission and review, and support launch and post-launch iteration. The best person for this role moves fluidly between code, product judgment, project leadership, and clear communication with engineers and executives. This role is a fit for a product minded engineer who wants to stay close to users and partners while still going deep on code, reliability, evaluations, and developer experience. The goal is to help partners ship plugins that are not merely technically functional, but genuinely useful in ChatGPT and Codex. This role is based in our San Francisco office. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Own the technical partner journey for priority B2B plugins—from pitch and readiness assessment through architecture, build, evaluation, submission, launch, and ongoing maintenance. Identify strong plugin use cases, define crisp user journeys and expected behaviors, and

About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem designed to accelerate customer success, enable enterprise AI adoption, and drive durable growth in support of OpenAI’s mission. We work closely across Product, Research, Sales, Legal, Communications, and regional leadership to ensure a cohesive strategy and disciplined execution with our most strategic partners. About the Role We are hiring a Partner Director, Global McKinsey Alliance to lead and scale OpenAI’s relationship with McKinsey & Company. This role will serve as the single accountable executive owner of the alliance globally. You will define the partnership strategy and operating model, translating executive alignment into scaled commercial and transformation outcomes across regions and industries. You will work closely with McKinsey’s global leadership, industry and functional practices, and technology organizations—including QuantumBlack, AI by McKinsey—to develop differentiated enterprise AI offerings, pursue complex transformation opportunities, and help customers move from strategy to production deployment and measurable value. The role carries responsibility for the health, performance, and long-term expansion of the partnership. Success requires senior executive presence, sound judgment, commercial discipline, technical fluency, and the ability to operate effectively across a complex, partner-led organization. In this role, you will: Own the global McKinsey relationship, including alliance strategy, pipeline growth, enterprise impact, deployment scale, and long-term expansion across priority industries. Define and run the partnership’s operating model across executive governance, joint planning, regional execution, opportunity management, resource allocation, and escalation. Serve as OpenAI’s senior executive counterpart to McKinsey’s global leadership and relevant industry, functional, technology, and regional leaders. Develop a differentiated alliance s

About the team The Partnerships team supports OpenAI’s mission by building and managing external relationships that expand product reach, accelerate adoption, strengthen strategic capabilities, and help the company scale responsibly. We partner across the organization to develop ecosystem strategy, create shared value, and support relationships that are critical to OpenAI’s growth. About the role We’re looking for a Partnerships Manager to lead high-impact relationships across technology, product, go-to-market, and operations. You’ll manage a portfolio of strategic external partners—including technology platforms, distribution channels, service providers, and other ecosystem partners—and work closely with internal teams to turn business needs into effective partnership strategies. This role combines relationship management, commercial judgment, and hands-on execution. You’ll help evaluate new partners, negotiate agreements, improve existing programs, and create the operating mechanisms needed to manage partnerships at scale. This role is based in San Francisco or New York in office 3 days a week. In this role, you will Own and deepen relationships with key strategic and ecosystem partners. Develop partnership strategies aligned with OpenAI’s product, go-to-market, and operational priorities. Source, evaluate, and onboard new partners and service providers. Lead commercial negotiations in partnership with Legal, Business Operations, Procurement, Security, and other stakeholders. Translate complex business requirements into clear partner selection criteria and operating plans. Establish performance metrics, governance processes, and regular business reviews for strategic relationships. Identify opportunities to improve economics, service quality, resilience, and scalability across the partner portfolio. Coordinate cross-functional initiatives involving Sales, Product, Engineering, Legal, Security, Marketing, Business Operations, and other partner-facing teams. Monitor

About the Role As an Account Director for Higher Education in AMER, you will own strategic relationships with colleges, universities, and higher education systems as they move from AI experimentation to responsible, institution-wide transformation. You will work with presidents, provosts, CIOs, CTOs, academic and administrative leaders, researchers, security teams, and procurement stakeholders to define priority use cases, build the technical and governance foundation for deployment, and translate institutional goals into a multi-year AI transformation roadmap. You will own the commercial and customer journey end to end—from territory strategy, pipeline creation, and executive alignment through evaluation, procurement, deployment, adoption, consumption, value realization, and expansion. This is a deeply technical, consultative sales role. You will be expected to understand AI capabilities and limitations, integration patterns, data governance, privacy, security, and change management; partner effectively with technical experts; and remain accountable for measurable customer and revenue outcomes after signature. In this role, you will: Own and execute the AMER higher education territory and account strategy, prioritizing institutions where OpenAI can support meaningful, responsible, and scalable transformation. Create pipeline and lead complex, multi-threaded new-business and expansion opportunities from first engagement through procurement, deployment, adoption, and value realization. Engage credibly with presidents, provosts, CIOs, CTOs, academic leaders, researchers, administrators, security teams, legal, procurement, finance, and end-user champions. Lead cross-functional pursuit and account teams across Solutions Engineering, Customer Success, Product, Research, Security, Legal, and other functions to design evaluations, pilots, technical validation, executive business cases, production deployments, and adoption plans. Translate AI model and platform capabilities

About the Team The Intelligence and Investigations team seeks to rapidly identify and mitigate abuse and strategic risks to ensure a safe online ecosystem. We are dedicated to identifying emerging abuse trends, analyzing risks, and working with our internal and external partners to implement effective mitigation strategies to protect against misuse. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits humanity. The Strategic Intelligence & Analysis (SIA) team provides safety intelligence for OpenAI’s products by monitoring, analyzing, and forecasting real-world abuse, geopolitical risks, and strategic threats. Our work informs safety mitigations, product decisions, and partnerships, ensuring OpenAI’s tools are deployed securely and responsibly across critical sectors. About the Role As a Quantitative Intelligence Analyst , you will focus on discovering novel and emerging risks in complex human–AI systems before they are well-defined, measurable, or widely understood. You will use deep subject matter expertise and quantitative tooling to surface weak, early, and unconventional risk signals. You will build analytic models that explain how harms could emerge and translate ambiguous patterns into structured, data-driven insight. Your work will help identify potential gaps in policy or coverage and operationalize previously unmeasured problems into signals that can support detection, mitigation, and planning downstream. You will develop analytical frameworks that map how new risks form, evolve, and propagate as products change, policies shift, and external events unfold. Your analyses will directly inform strategic risk prioritization and planning across the company, with regular visibility through strategic risk products. This role is based in office (hybrid, 3 days/week). Relocation support is available In this role, you will: Discover and define new quantitative risk signals where no established metrics exist, using subject matter exp

About the Team OpenAI’s API Multicloud team is responsible for extending OpenAI’s API platform into strategic cloud environments, starting with AWS . The team’s mission is to distribute OpenAI’s API broadly and safely by enabling key API technologies in cloud-native environments, in close partnership with Amazon and internal teams across Codex, Research, Safety Systems, and Applied. The team is focused on bringing core developer and enterprise capabilities into cloud-native environments, including cloud-hosted Codex, model customization / post-training as a service, and new stateful runtime environments for agentic workloads. This work sits at the intersection of production ML systems, developer platforms, model behavior, and large-scale infrastructure. About the Role We’re looking for a backend engineer who can quickly understand OpenAI’s models, products, and systems, then adapt first-party deployments for other cloud platforms. You’ll build backend services, APIs, SDK integrations, authentication flows, and cloud service infrastructure that let developers use OpenAI capabilities in the cloud environments where they already build. This role involves working across teams, sometimes embedded with partner product groups, to ship products quickly and across multiple platforms at the same time. It’s a strong fit for engineers who have built developer tools, especially AI-powered tools, communicate clearly across technical boundaries, and can shape architectures that support different deployment models; experience building cloud services is a strong plus. In this role, you will: Build backend and infrastructure systems that extend OpenAI’s API platform into cloud-native environments, like AWS. Design and ship cloud-contained products that allow customers to use OpenAI capabilities while keeping workloads and data within cloud environments. Help stand up cloud-hosted Codex experiences powered by the OpenAI Responses API. Build the infrastructure and runtime abstractions

About the Team The Intelligence and Investigations team seeks to rapidly identify and mitigate abuse and strategic risks to ensure a safe online ecosystem. We are dedicated to identifying emerging abuse trends, analyzing risks, and working with our internal and external partners to implement effective mitigation strategies to protect against misuse. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits humanity. The Strategic Intelligence & Analysis (SIA) team provides safety intelligence for OpenAI’s products by monitoring, analyzing, and forecasting real-world abuse, geopolitical risks, and strategic threats. Our work informs safety mitigations, product decisions, and partnerships, ensuring OpenAI’s tools are deployed securely and responsibly across critical sectors. About the Role As an Agentic Risk Analyst, you will shape OpenAI’s operating picture for current agentic risk across products and platforms. You will bring a strategic, system-level perspective to current risks, connecting individual incidents, technical findings, abuse patterns, and external developments to relevant workstreams, mitigations, owners, dependencies, and residual gaps. You will analyze how risks emerge through autonomy, multi-step task execution, tool use, memory, retrieval, connectors, computer-use capabilities, and multi-agent workflows, with a particular focus on both adversarial misuse and unintended system behavior. By synthesizing signals from investigations, evaluations, red teaming, security reviews, product launches, external research, and real-world incidents, you will maintain a current view of material risks and evolving threat patterns. Your work will help turn complex and often ambiguous signals into coordinated decisions and measurable follow-through across product, safety, security, policy, and governance teams. You will work closely with investigators, engineers, product, policy, safety, and security teams, and measurement and forecasting

About the team The Intelligence and Investigations team seeks to rapidly identify and mitigate abuse and strategic risks to ensure a safe online ecosystem in close collaboration with our internal and external partners. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits humanity. This role focuses specifically on AI Safety: understanding and mitigating risks created or amplified by increasingly capable AI systems. It is not a cybersecurity, information security, or corporate security role. The Strategic Intelligence & Analysis (SIA) team provides safety intelligence for OpenAI’s products by monitoring, analyzing, and forecasting real-world abuse, geopolitical risks, and strategic threats. Our work informs AI safety mitigations, product decisions, and partnerships, ensuring OpenAI’s tools are deployed responsibly across critical sectors. About the role We are looking for a Frontier AI Risks Lead to help us understand potential harms and misuse of AI in a time of rapid, sustained change. We seek to understand how developments in AI could intersect with misuse and abuse, accelerating existing harm areas and creating novel risks. We seek to scan available signals and use strategic foresight methodologies to enable proactive detection and mitigation of frontier AI risks. This is an AI safety role focused on frontier and systemic risks, including model misalignment, recursive self-improvement (RSI), multi-agent interaction, loss of control, runaway agents, and related emerging failure modes. In this role, you will help provide a strategic-level perspective on a range of frontier AI safety areas, producing actionable understanding of issues relevant to OpenAI’s platforms, systems, and broader mission. Utilizing mixed quantitative and qualitative methodologies, you will spot early warning signs, pull threads on potentially concerning behavior, and turn weak signals into clear, prioritized risk calls. You will focus on upstream ecosystem sc

About the Team OpenAI’s API Multicloud team is responsible for extending OpenAI’s API platform into strategic cloud environments, starting with AWS . The team’s mission is to distribute OpenAI’s API broadly and safely by enabling key API technologies in AWS-native environments, in close partnership with Amazon and internal teams across Codex, Research, Safety Systems, and Applied. The team is focused on bringing core developer and enterprise capabilities into cloud-native environments, including AWS-hosted Codex, model customization / post-training as a service, and new stateful runtime environments for agentic workloads. This work sits at the intersection of production ML systems, developer platforms, model behavior, and large-scale infrastructure. About the Role We’re hiring Machine Learning Engineers to build and improve the AI systems that help strategic partners adapt OpenAI models to important use cases in cloud-native environments. This role spans post-training workflows, evaluation, data pipelines, model behavior, and API/infrastructure integration. You’ll work at the boundary between partner needs and core ML systems: helping teams understand what is and isn’t working, diagnosing issues in training and evaluation workflows, and turning those learnings into improvements to the underlying platform. You should enjoy working with external technical partners, extracting the real goal from messy requests, and pushing back or reframing when the requested experiment is not the highest-leverage path. You’ll collaborate closely with Research, Applied, Safety Systems, infrastructure teams, and external technical partners to solve ambiguous model-performance problems. When you succeed, strategic partners and internal teams will be able to improve model behavior with confidence, driving measurable product improvements while the systems behind that work become more reliable, scalable, and effective over time. In this role, you will Partner with strategic customers and in

About the Team OpenAI's Industrial Compute organization is building and scaling the infrastructure required to support frontier AI. The Infrastructure Strategic Sourcing team connects technical and project requirements to supplier readiness, contracting, purchasing, equipment delivery, and portfolio-level risk visibility across owner-furnished contractor-installed equipment (OFCI), data center networking, rack systems and integration, fiber, cabling, optical interconnects, and related infrastructure. The team partners across Pre-Construction, Design, Construction, Electrical and Mechanical Engineering, Network Engineering, Hardware and Rack Delivery, Strategic Sourcing, Procurement, Legal, Finance, Accounts Payable, Logistics, and external suppliers. We build the operating mechanisms that keep sourcing decisions, purchase execution, long-lead equipment, network and fiber dependencies, rack readiness, and delivery commitments aligned to infrastructure schedules. About the Role We are seeking an Infrastructure Sourcing Operations Lead to own procurement operations across pre-construction, design, construction, and sourcing through purchase order issuance, while maintaining visibility through invoice resolution, production, logistics, delivery, installation, and readiness. The portfolio includes electrical and mechanical OFCI, networking equipment, rack systems and integration, fiber, cabling, optical interconnects, and other infrastructure required to bring capacity online. In this role, you will set priorities, make or escalate decisions that affect cost, supplier relationships, contractual position, and delivery schedules, and define the standards used by execution support for queue management, documentation, tracker maintenance, and recurring reporting. Success requires sound commercial and program judgment, operational rigor, systems thinking, and the ability to turn incomplete information across vendors, tools, and project teams into clear decisions, accountable

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. Our Communications team includes External Communications, Internal Communications, and other strategic communications functions. This team’s ethos is to support OpenAI’s mission and goals by clearly and authentically explaining our technology, values, and approach to safely building powerful AI. About the Role We’re looking for a senior communications leader to shape how OpenAI communicates about cybersecurity. This person will define the global narrative, lead communications for major product, research, and business milestones, and build sustained programs that explain how OpenAI is helping advance cyber defense while managing the risks created by increasingly capable models. The role will connect OpenAI’s work across cybersecurity products and capabilities, responsible deployment, threat intelligence, enterprise security, research, and public policy. You will work closely with Security, Product, Research, Preparedness, Safety, Global Affairs, Go-to-Market, Legal, and Marketing to anticipate opportunities and risks, develop coordinated communications, and build trust with security practitioners, customers, policymakers, and the public. This is both a strategic and hands-on role. The right person will be comfortable defining a long-term communications strategy, building the systems and relationships needed to execute it, and personally leading through major launches, technical disclosures, and fast-moving issues. This role reports to the Head of Communications, Business and is based in San Francisco, CA. We use a hybrid work model of 3 days per week in the office and offer relocation assistance. In this role, you will: Define and lead communications strategy for OpenAI’s cybersecurity work, from global narrative development through launches, research, threat reporting, and sustained storytelling. Build a clear, differentiated story about how OpenAI can

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. The Business Marketing team contributes to our broader mission of ensuring responsible and widespread adoption of artificial intelligence by developing and executing strategies that drive awareness, engagement, and usage for OpenAI’s products and platform amongst core business audiences. The Strategy & Operations function supports Business Marketing with operating models and cadences; strategic planning; portfolio, resource, and investment management; measurement and organizational learning that empower our teams to move at pace with clarity and confidence. This is a hybrid role, based in San Francisco Bay Area (preferred) or New York City three days a week. About the Role Business Marketing moves quickly, and this role sits close to the work. We’re looking for an analytical, highly collaborative Business Operations Manager who can turn a complex marketing budget into better day-to-day decisions. You will partner with marketing leaders, Strategic Finance, Procurement, Data Science, agencies, and regional teams to plan and pace spend, manage commitments, answer urgent questions, and translate investment data into clear actions. This role is not for someone who prefers back-office operations. You will be embedded in the business, understand what teams are trying to achieve, and help them move faster with confidence. You will run the operating rhythm for budget administration across a global, highly matrixed team: maintaining a trusted view of allocations, POs, contracts, actuals, forecasts, and risks; reconciling inputs across different marketing functions, regions, and shared services; and surfacing tradeoffs for leadership and Strategic Finance. You will also partner with Data Science to better connect spend to outcomes, lead useful ad hoc analysis, and build AI-enabled tools and workflows that take the friction out of budget management and make th