Technical Principal Jobs

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role Join Anthropic's Customer Success team in a high-visibility & high-impact role driving AI adoption across a small number of enterprise accounts in our Enterprise Tech segment. As our dedicated Customer Success Manager for Enterprise Tech Customers you’ll be their partner and trusted advisor helping them harness the full potential of all our Claude capabilities - API, Claude Code, Cowork, and other surface areas. You'll work with a book of global technology leaders to actively deploy AI and reshape the technology landscape. You’ll be working with key partners who are moving fast and pushing the boundaries of what's possible with LLM technology. Your role will entail developing genuine partnerships with the customer and key stakeholders, gaining a deep understanding of their multi-pronged business objectives, strategic direction, AI vision, and technical needs. You'll draw on both your business acumen and technical expertise to serve as a strategic advisor throughout their journey with us. In partnership with the broader account team, you will help customers identify the right Claude capabilities for their specific business objectives, working closely with them to provide best practices and guidance while supporting them as their usage grows and evolves. Your role focuses on helping customers scale their usage effectively, drive model and use case optimizations, implement change management strategies, and maximize the value of their investment through expanded use cases across their organization. The insights you gather from your customers will directly inform our research priorities, product development, and go-to-ma

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About The Anthropic Institute The Anthropic Institute (TAI) is a function within Anthropic that works to advance the public conversation around AI. The Institute is comprised of research teams tackling some of AI's most consequential societal challenges: the Frontier Red Team, which stress tests our systems against catastrophic risks; Societal Impacts, which studies how Claude is used by millions of people; Economic Research, which tracks AI's impact on people's jobs and the larger economy; the Rule of Law team, which studies AI's impacts to democracy; and more. The Institute's mission is to reduce information asymmetries between Anthropic and the outside world, name and answer the hard questions implied by powerful AI systems, and publish these findings so that policymakers, researchers, technology leaders, and the public can reckon with what's here and what's to come. About the role The role. You will build and lead the Institute’s tabletop exercise program and the team that runs it. Based on trends visible in the exponential and in consultation with technical experts, you will set the research agenda: which questions the exercises should answer, which scenarios to run, with which audiences, and what each run is meant to test. You will own the methods that make results comparable across runs and turn them into findings people outside the room can use. You will hire and manage a team plus a bench of facilitators, and you will be the program’s public voice. Why tabletop exercises? If RSI arrives, the hardest problems will be about making decisions under uncertainty. The people making them may not trust each other, and the author

JLL empowers you to shape a brighter way . Our people at JLL are shaping the future of real estate for a better world by combining world class services, advisory and technology for our clients. We are committed to hiring the best, most talented people and empowering them to thrive, grow meaningful careers and to find a place where they belong. Whether you’ve got deep experience in commercial real estate, skilled trades or technology, or you’re looking to apply your relevant experience to a new industry, join our team as we help shape a brighter way forward. What this job involves: Technician will involve in the overall upkeep of plant and facilities equipment to ensure smooth daily operations. He/she needs to regularly inspect all equipment rooms and other facilities, and take note of any problem using the predefined checklists. Key Responsibilities : Conduct daily inspections of all equipment rooms and facilities to identify issues, using predefined checklists. Guide duty technicians on weekend work plans and provide technical recommendations as needed. Perform repairs on mechanical and electrical systems while adhering to safety protocols. Coordinate with vendors for urgent maintenance tasks and ensure timely resolution. Expedite equipment relocations, installations, and modifications (MACs) to minimize operational disruptions. Ensure compliance with local government regulations in all maintenance activities. Qualifications & Skills : Certification in electrical or mechanical repair (e.g., HVAC, PLC systems). Proven experience in facilities maintenance or a similar role. Ability to diagnose issues, troubleshoot effectively, and provide clear instr

About the Team Dots is building personal AI agents that help people make progress on their goals, including when they are away from ChatGPT. These agents can learn preferences, maintain context, work across applications, and use cloud computers to carry out tasks. Our team brings together product engineering, design, and research to turn frontier model capabilities into useful everyday experiences. We are defining how people delegate work, understand what an agent is doing, and stay in control. Engineers help shape both the product and the systems behind it, from early prototypes through launch and iteration. About the Role We are looking for Senior and Staff Full Stack Software Engineers to build Dots product experiences from the interface through the services that power them. You will help define how people delegate tasks to personal agents, follow their progress, and collaborate with them over time. This role combines hands-on product development with the systems work needed to make persistent, asynchronous agent experiences reliable. In this role, you will: Build and launch features across web interfaces, APIs, backend services, and data models. Create workflows for task creation, progress updates, agent feedback, and results that remain coherent across sessions and devices. Translate emerging model capabilities into product prototypes with research, product, and design partners. Design clear interfaces between product surfaces and agent execution systems. Improve performance and reliability across the stack, including user-facing latency and recovery from partial failures. Own projects from early exploration through architecture, implementation, launch, and iteration based on user feedback. Help establish technical direction, testing practices, and observability as the product grows. You might thrive in this role if you: Have significant experience building and shipping products across frontend and backend systems. Can move comfortably between user interfaces,

About the Team Dots is building personal AI agents that help people make progress on their goals, including when they are away from ChatGPT. These agents can learn preferences, maintain context, work across applications, and use cloud computers to carry out tasks. Our team brings together product engineering, design, and research to turn frontier model capabilities into useful everyday experiences. We are defining how people delegate work, understand what an agent is doing, and stay in control. Engineers help shape both the product and the systems behind it, from early prototypes through launch and iteration. About the Role We are looking for Senior and Staff Software Engineers to build the mobile web experience for Dots. You will create responsive, accessible interfaces that let people start work, follow progress, and guide their agents from a phone or browser. You will help establish interaction patterns for ongoing, asynchronous work and make sophisticated agent capabilities feel clear and approachable. In this role, you will: Design and ship mobile web experiences for creating tasks, reviewing agent activity, and providing feedback or direction. Build interfaces that handle streaming updates, long-running tasks, interrupted sessions, and changing connectivity. Improve responsiveness, loading performance, accessibility, and usability across screen sizes and browsers. Partner with design and product to prototype interaction patterns that give users visibility and control over agent actions. Work with backend and full stack engineers on APIs, client state, and reliable synchronization between the interface and agent services. Own features from exploration and technical design through launch, measurement, and refinement. Help set frontend architecture and engineering practices while staying hands-on with implementation. You might thrive in this role if you: Have substantial experience shipping polished web applications, with deep expertise in mobile web development

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. Within Safety Systems, the Model Policy team works to ensure that frontier models behave safely and reliably in real-world environments by designing policies that define safe model behavior. We've had several relevant publications, including: Safety at every step OpenAI GPT6 System Card OpenAI Model Spec About the Role We’re hiring a Model Policy Manager to shape model behavior for U.S. government use, with a focus on national security applications. You’ll define nuanced policies and translate them into training and evaluation criteria, helping models navigate high-stakes scenarios while preserving their usefulness and capabilities. In this role, you’ll: Develop model policies that guide safe and useful behavior. Build evaluations, identify policy gaps and model failures, and use findings to improve policies and training. Work with research, engineering, and domain experts to support safe, reliable deployment. You might thrive in this role if you: Bring relevant experience in AI safety, policy, or risk assessment. Have strong judgment and can turn complex safety questions into clear, practical policies. Have the technical fluency to work hands-on with model data and evaluations. Are motivated by OpenAI’s mission and the re

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview About the Role - As a Senior Sales Engineer at Instacart, you'll have a unique opportunity to drive adoption of our flagship, industry leading ecommerce products and services directly to the largest retailers in North America and across the globe. This role requires you to lead consultative, technical-focused discussions with external and internal stakeholders, supporting new implementations and integrations. With your expertise, you'll guide customers through the sales cycle, providing both technical and product knowledge. Collaborating with cross-functional teams will give you a holistic understanding of Instacart's technical capabilities. About the Team - You’ll join our Sales Engineering team, working at the intersection of Business Development, Product, Engineering, and Enterprise Solutions. We collaborate as one team to bring Instacart’s ecosy

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview About the Role - As a Senior Sales Engineer at Instacart, you'll have a unique opportunity to drive adoption of our flagship, industry leading ecommerce products and services directly to the largest retailers in North America and across the globe. This role requires you to lead consultative, technical-focused discussions with external and internal stakeholders, supporting new implementations and integrations. With your expertise, you'll guide customers through the sales cycle, providing both technical and product knowledge. Collaborating with cross-functional teams will give you a holistic understanding of Instacart's technical capabilities. About the Team - You’ll join our Sales Engineering team, working at the intersection of Business Development, Product, Engineering, and Enterprise Solutions. We collaborate as one team to bring Instacart’s ecosy

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role Axsome Therapeutics is seeking an Associate Director, IT Business Solutions to join the Information Technology team. This hands-on role requires deep cross-domain knowledge of broadly defined Corporate Systems and is responsible for both functional business and technical systems activities. The incumbent will partner closely with business stakeholders and IT teams to enhance technology solutions by translating high-level epics and user stories into actionable product backlogs, supporting testing efforts, and serving as a project lead or subject matter expert as needed. This individual will also manage select escalated post-implementation support issues and coordinate vendor engagement when appropriate to ensure timely and effective issue resolution. Leveraging strong domain and systems expertise, the Senior Manager will identify and drive opportunities for business transformation through system enhancements, process simplification, and

About the Team The Intelligence & Investigations Engineering team builds systems that detect, analyze, and disrupt abuse across OpenAI’s products. We partner closely with the Child Safety team and cross-functional groups to protect users while advancing OpenAI’s goal of developing AI that benefits everyone. About the Role As a Fullstack Engineer focused on child safety, you’ll build data-intensive, AI-powered applications and infrastructure that enable operators and investigators to work effectively and responsibly. You’ll adapt quickly in ambiguous, fast-moving environments to deliver well-crafted, reliable tooling for high-severity safety work. *Candidates should understand this role involves exposure to sensitive and egregious content. In this role, you will: 7+ years of experience as a software engineer Prototype, build, and maintain intelligence systems that detect, triage, and enable efficient human review of possible high severity harm Work hand in hand with operators and investigators, designing and delivering systems that enable them to do their work faster, more accurately, and more safely. Develop across the stack: UIs, services, pipelines, and anything else required to solve the problems we face. Interact with partners across Product Policy, Platform Integrity, Safety Systems, and Research Contribute to the team’s technical strategy, especially for child safety related tools and systems Report on impact in a data-driven fashion You might thrive in this role if you: Have a strong software engineering foundation and enjoy owning systems end-to-end—from infrastructure and data ingestion to frontend tooling Are energized by working at the frontier of AI capabilities, integrating new models and APIs into practical systems Have experience building and operating large-scale data pipelines or search/retrieval systems Are proficient in Python and/or TypeScript, and familiar with tools like Spark, Kafka, Flink, data warehouses, and SQL Take a product-minded ap

Territory: Bay Area, San Francisco, Oakland, Sacramento and surrounding areas POSITION SUMMARY We are seeking experienced clinical sales leaders with five or more years of proven success in diagnostics or specialty laboratory services to join our Rare Disease team. The Rare Disease Specialist (RDS) will be both a frontline sales driver and a strategic business partner, leading market expansion and shaping how we launch and grow our exome and genome testing portfolio across the U.S. As a Rare Disease Specialist, you will focus on engaging key clinical stakeholders, including developmental pediatricians, pediatric neurologists, genetic counselors, and medical geneticists, to drive awareness and adoption of our exome and genome testing solutions. This role is designed for high performers who excel at complex clinical sales, thrive in entrepreneurial environments, and want to leave a lasting mark on the rare disease landscape. PRIMARY RESPONSIBILITIES Own revenue growth and market development by driving direct sales to developmental pediatricians, pediatric neurologists, genetic counselors, and medical geneticists. Lead new product launches and accelerate the adoption of clinical exome and genome testing solutions. Build and sustain high-value relationships across Children’s Hospitals, rare disease networks, and clinical decision-makers. Design and execute territory business plans, with a clear focus on revenue acceleration and market share capture. Drive proposal development, pricing strategy, and contract negotiations to secure new business and formalize partnerships. Engage executive leadership with pipeline insights, opportunity prioritization, and performance metrics tied to rare disease growth. Serve as a clinical and technical resource, delivering education and training for providers and staff. ​ KNOWLEDGE, SKILLS, AND ABILITIES Demonstrated success selling into Children’s Hospitals and/or rare disease markets. Track record of winning new business an

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . As a Senior Machine Learning Engineer on the CX Intelligence Engineering team within Coinbase's Customer Engagement and Experience org, you'll design and build the AI-powered systems that connect our Help Center, chatbots, and agent workflows. This team owns the multi-agent platform powering Coinbase chat, Help Center, and agent tooling surfaces, partnering with Conversation Design, CX, and Engineering teams to deliver secure, compliant, and scalable AI support. You'll drive key CX automation initiatives, including multi-agent framework development, agent assist capabilities, and LLM-powered secure actions that help customers get answers faster while enabling human agents to resolve cases more effectively. What you'll do: Architect and deploy the multi-agent framework for agent assist, internal SOP execution, and secure LLM-powered actions, building scalable systems that handle millions of customer interactions. Own end-to-end project execution for complex ML initiatives, managing priorities, technical trade-offs, and cross-functional dependencies from design through production delivery. Build and optimize AI-driven concierge chat and agent copilot experiences that improve automated resolution rates and reduce case handling time. Develop systems to detect and manage bad actors and adversarial inputs, ensuring the multi-agent platform maintains high confidence and saf

About Datadog We're on a mission to build the best platform in the world for engineers to understand and scale their systems, applications, and teams. We operate at a high scale - trillions of data points per day — providing always-on alerting, metrics visualization, logs, and application tracing for tens of thousands of companies. Our engineering culture values pragmatism, honesty, and simplicity to solve hard problems the right way. The Opportunity User safety and platform integrity is critical to our business. Our customer’s success is our success. We’re looking for a Senior Security Engineer to join us in taking a proactive, highly scalable, and data-centric approach to enabling a safe and trustworthy experience for the users of our rapidly growing and increasingly interactive platform. You’ll fight against threats to our users, platform abuse, and other potentially risky and unwanted behaviors on our platform. Our team covers a broad range of trust and safety related topics including software engineering, data science, user engagement, privacy, threat detection, incident response, and bridging gaps between security and the broader Datadog business. You will bring expertise in a few of these areas. You’ll join a growing security team at an ideal time for making a big impact. Datadog is growing rapidly, and AI-assisted development is increasing both the pace of software delivery and the amount of activity generated by AI agents. The product is seeing very high growth, with the platform becoming more interactive and new products and features developed regularly. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Have a direct impact on customers and their overall trust of our platform. Drive the technical roadmap in colla

About Appspace: At Appspace, we’re passionate about creating better work experiences for people everywhere, and we’re looking for people that feel the same way. Our global office locations and flexible work culture help you work wherever and however you’re at your best. Plus, we take the time to help you enjoy your work, build lasting connections, and grow your role. Join the Appspace team and be a part of a culture that’s helping people everywhere love where they work. Your Role as an Intranet Account Executive : Our Intranet Account Executive are dynamic, engaging, and entrepreneurial. They are responsible for driving strategy, planning, and executing sales of Appspace’s Employee Comms Solution to Appspace customers and prospective customers. By working closely with our strategic partners and channel community, and partnering with other Appspace AE’s or directly selling to buyers, the AE will drive revenue growth through ongoing pipeline development and deal-winning activities. The successful candidate should be comfortable in customer, prospects and partner-facing roles and possess strong presentation skills, technical acumen, and the drive to win. This is a sales role and a peer position to our current Account Executives with an individual quota and commission plan and not an “overlay” position. A Day in the Life of an Intranet Account Executive : Take a leadership role specifically driving Appspace Employee Comms sales for your assigned territory Target accounts to acquire as new Appspace customers as well as upselling and cross-selling to existing accounts working closely with those account teams. Be the go-to expert on Appspace in a collaborative sales approach with strategic technology and channel partners helping enhance existing partners and drive new relationships working closely with our partner team. Build and execute on an innovative business plan with our strategic partners and channel community to meet and exceed customer need

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the Role Anthropic's Executive Briefing program brings senior leaders from our most strategic customers together with our spokespeople, product leaders, and researchers. As a Program Manager, Executive Briefings, you will run the program at one of our briefing centers and help build the global operating model that ensures an exceptional and consistent experience across the globe. You will be the main program lead for your location and own briefings end to end: qualification and intake, agenda design, speaker selection, and day-of execution. You will set the objectives and design for each agenda and develop it jointly with Sales. You will also be the local account teams' go-to partner on how to use a briefing to move their most important opportunities forward. You will manage the global workstream and set the standard every center follows, so customers get the same quality of briefing wherever they meet us. This is a highly cross-functional role. You will work with regional GTM leadership and the Office of the CCO on account selection and program strategy, with Product Marketing on content, with Solutions on technical deep-dives and demos, with Anthropic's executive bench on sponsorship and participation, and with Workplace, Security, and Revenue Operations on the experience and systems behind every briefing. You will be comfortable running every part of a briefing yourself and maintaining tight alignment with internal stakeholders. Key responsibilities Own the Executive Briefing program at your location: the local calendar, capacity planning, the request and intake process from Sales, and operating SLAs, applied against global c